OBJECTIVES This study was performed to validate the clinical usefulness of measuring the time difference between onset of mitral inflow and onset of early diastolic mitral annulus velocity (T(E'-E)) for the evaluation of left ventricular (LV) diastolic function. BACKGROUND In recent studies, T(E'-E) correlated well with the time constant of LV pressure decay (tau), and the ratio of IVRT/T(E'-...

Objective To assess whether high levels of cerebrospinal fluid neurogranin are found in atypical as well as typical Alzheimer's disease. Methods Immunoassays were used to measure cerebrospinal fluid neurogranin in 114 participants including healthy controls (n = 27), biomarker-proven amnestic Alzheimer's disease (n = 68), and the atypical visual variant of Alzheimer's (n = 19) according to in...

Reaching towards a visual object in the absence of visual referents relies on a chain of information, from the sensory signals encoding the object's image on the retina, to the motor signals driving the hand. One link in this chain is an extraretinal eye position signal (EEPS), which specifies the position of the eye in the head. EEPS must be updated in precise coordination with the eye's rapid...

a topoframe, denoted by $l_{ tau}$,  is a pair $(l, tau)$ consisting of a frame $l$ and a subframe $ tau $ all of whose elements are complementary elements in$l$. in this paper, we define and study the notions of a$tau $-real-continuous function on a frame $l$ and the set of realcontinuous functions $mathcal{r}l_tau $ as an $f$-ring.we show that $mathcal{r}l_{ tau}$is actually a generalization ...

The problem of parameterized range majority asks us to preprocess a string length n such that, given the endpoints range, one can quickly find all distinct elements whose relative frequencies in that are more than threshold \(\tau\). This is tractable version classical finding mode, which unlikely be solvable polylogarithmic time and linear space. In this paper we give first linear-space soluti...

The purpose of this paper is to study the distribution zeros solutions a first-order neutral differential equation form \begin{equation*} \left[x(t) + p(t) x(t-\tau)\right]' q(t) x(t-\sigma) = 0, \quad t \geq t_0, \end{equation*} where $p\in C([t_0,\infty),[0,\infty))$, $q \in C([t_0,\infty),(0,\infty))$, $\tau,\sigma>0$, and $\sigma>\tau$. We obtain new upper bound estimates for distance betwe...

For functions \(f: \mathcal {P}\mapsto \mathbb {C}\) on partitions, Bloch and Okounkov defined a power series 〈f〉q that is the “weighted average” of f. As Fourier in q = e2πiz, such q-brackets generate ring quasimodular forms, modular forms are powers Dedekind’s eta-function. Using work Berndt Han, we build objects from $$\displaystyle f_t(\lambda ):= t\sum _{h\in {H}_t(\lambda )}\frac {1}{...

BACKGROUND The pathologic substrates of frontotemporal dementia (FTD) are difficult to predict in vivo. OBJECTIVE To determine whether different pathologic substrates of FTD have distinct patterns of regional atrophy on magnetic resonance imaging (MRI). DESIGN Retrospective case study. SETTING The Institute of Neurology, University College London, and the Institute of Psychiatry, King's C...

Recent studies report that depletion and repletion of muscle taurine (Tau) to endogenous levels affects skeletal muscle contractility in vitro. In this study, muscle Tau content was raised above endogenous levels by supplementing male Sprague-Dawley rats with 2.5% (wt/vol) Tau in drinking water for 2 wk, after which extensor digitorum longus (EDL) muscles were examined for in vitro contractile ...