Marfan syndrome (MFS) is a genetic disorder which is inherited by autosomal dominant traits. In MFS, lens displacement and cardiovascular involvement are important causes of morbidity and mortality in the clinical course of the disease. In this case study, the ocular involvement in a family with severe penetration of MFS is reported. Twelve members of a family (father, two daughters, three sons...

Background: Ceftriaxone is an antibiotic used for treating respiratory,skin,bone and kidney infections. Our purpose was investigating effect of ceftriaxone on testicular tissue. Materials and Methods: 40 mice with 6 weeks old were used in this study. The mice randomly were divided into 2 groups, control- sham and test groups. The test group was subdivided to IP1 and IP2 which received Ceftriaxo...

purpose: to compare aspheric and spherical hydrophilic intraocular lenses (iols) in terms of contrast sensitivity and visual acuity in photopic and mesopic conditions. methods: this triple-blind randomized clinical trial was performed on 40 eyes of 40 patients at al-zahra eye center, zahedan, iran. the eyes were randomized to standard phacoemulsification procedure with spherical (adapt, b&l;) o...

the aim of this study was to report a new cause of cataract, namely snake bite induced cataract in a dog. a 3-year-old male mongrel dog was referred to our clinic for the assessment of cataract in both eyes. the dog was bitten by a snake nearly 4 months ago. a 40 dioptre acrylic lens with 13 mm haptics was implanted into the lens capsule. in the left eye, posterior synechia was detected in the ...

background: wearing spectacles is the most common approach in correcting the refractive errors worldwide. due to harmful effects of overexposure to solar ultraviolet radiations, the usage of multi-layer coatings in ophthalmic lenses has recently been increased. these lenses can reduce the reflections and hence increase the transmission of visible light; they can also decrease the transmission o...

PURPOSE We estimated the contribution of the gradient refractive index (GRIN) and lens surfaces to lens astigmatism and lens astigmatic angle as a function of age in human donor lenses. METHODS Human lenses were imaged, ex vivo, with 3D-spectral optical coherence tomography (OCT) and their back focal length was measured using laser ray tracing. The contribution of lens surfaces and GRIN to le...

purpose: to report three cases of alport syndrome in one  family with anterior lenticonus and retinal flecks. patients and findings: three members of one family with consanguineous parents are presented who had renal and ocular involvement. they had anterior lenticonus and a beaten bronze appearance in the macula. reduced visual acuity and photophobia were the chief complaints of these patients...

Background: Palliative whole brain radiotherapy (WBRT) has been the standard treatment for brain metastases. Ionizing radiation is known to be one of the most potent cataractogenic agents. We aimed to evaluate two different radiotherapy techniques with respect to the doses received by the organs at risk (OAR) in patients with brain metastasis who undergone WBRT. Materials and Methods: Ten conse...

The eye lens consists of a layer of epithelial cells that overlay a series of differentiating fiber cells that upon maturation lose their mitochondria, nuclei and other organelles. Lens transparency relies on the metabolic function of mitochondria contained in the lens epithelial cells and in the immature fiber cells and the programmed degradation of mitochondria and other organelles occurring ...

Introduction: Dental panoramic radiography (DPR) is one of the most frequent diagnostic X-ray procedures, the application of which is currently on a growing trend. During DPR, several radiosensitive tissues, such as the lens of the eyes, parotid gland, and thyroid gland, contribute to the radiation field, and it is necessary to monitor their received dose. The aim of t...