1. The susceptibility of mice to the lethal effect of preparations containing the oxygen-labile hemolysin (streptolysin O) of group A hemolytic streptococci has been studied. Injection of a single sublethal dose of the streptococcal preparation causes the development of resistance to the effect of a lethal dose injected subsequently. 2. Resistance is demonstrable 3 to 6 hours after the injectio...

Introduction: Adaptive response is one of the important concepts in radiobiology. The present report aimed to transfer the radio-adaptation via serum. Material and Methods: In total, 50 male adult Wistar rats were randomly divided into 6 groups, including control, serum control, low-dose (100cGy), low-dose/lethal, serum/lethal, and lethal (8G...

The intracellular pathogen Legionella pneumophila translocates a large number of effector proteins into host cells via the Icm/Dot type-IVB secretion system. Some of these effectors were shown to cause lethal effect on yeast growth. Here we characterized one such effector (LecE) and identified yeast suppressors that reduced its lethal effect. The LecE lethal effect was found to be suppressed by...

Aculeacin A was lethal for proliferating cultures of C. albicans. However, there was a paradoxical relationship between the drug concentration and the fungicidal activity; the lethal effect was greatest at levels of 0.08 to 1.25 microgram/ml and increases in the drug concentration above this range reduced its lethal effect. A similar anomalous dose-response patterns were also observed for the i...

for each media condition as the extent of survival and reproduction (fitness) of the deletion strain relative to the pool of all strains grown and measured collectively. Fitness values (f) of 1.0 indicate no difference between a single strain and the pool average for that condition; f , 1.0 indicates that the strain is less fit, and f . 1.0 indicates that the strain is more fit than the pool av...

The aim of this study was to evaluate the effect of walnut tree root (Juglandaceae) on Escherichia coli is resistant to various antibiotics. Walnut tree root extract was obtained using a rotary device. 20 cases of E. coli was obtained from urinary tract infections Zabul hospital and MIC and MBC were determined using dilution in the wells. The results of the study showed that the concentrations ...

The effect in alcoholic extract of Bark of Albizzia lebbeck was studied for antifilarial activity using Setaria cervi (S. cervi) worm procured from the freshly slaughtered buffalo.We used the whole worm (w.w.) preparation and nerve muscle (n.m.) complex of Setaria cervi (S. cervi). The n.m. complex is made by stripping the cuticle of the worm. The effect was stimulant in nature in both the prep...

The aim of this study was to evaluate the effect of walnut tree root (Juglandaceae) on Escherichia coli is resistant to various antibiotics. Walnut tree root extract was obtained using a rotary device. 20 cases of E. coli was obtained from urinary tract infections Zabul hospital and MIC and MBC were determined using dilution in the wells. The results of the study showed that the concentrations ...

melissa officinalis  is a well known medisinal plant.different studies performed in mice have shown the sedative.hyonotic,analgesic,antiviral amd antimicrobial effects of this plant.the present  investigation was undertaken to evaluate the effect of percolated extract of this plant against lethal seizure induced by intraperitional injection of pentylentetrazole (PTZ) in wister rats.the study wa...