The role of serum erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) as the first line for evaluating a patient with periprosthetic joint infection (PJI) has been debunked.We are living in the era of biomarkers for the diagnosis of PJI, and to that effect, several biomarkers have been introduced such as synovial fluid alpha defensin and leukocyte esterase.The synovial fluid leuko...

Background: Many studies have evaluated the accuracy of dipstick tests as rapid detectors of bacteriuria and urinary tract infections (UTI). The lack of an adequate explanation for the heterogeneity of the dipstick accuracy stimulates an ongoing debate. The objective of the present meta-analysis was to summarise the available evidence on the diagnostic accuracy of the urine dipstick test, takin...

BACKGROUND Many studies have evaluated the accuracy of dipstick tests as rapid detectors of bacteriuria and urinary tract infections (UTI). The lack of an adequate explanation for the heterogeneity of the dipstick accuracy stimulates an ongoing debate. The objective of the present meta-analysis was to summarise the available evidence on the diagnostic accuracy of the urine dipstick test, taking...

Abstract Background The purpose of the study is to evaluate performance and agreement rapid point-of-care (POCT) urine dipstick testing in emergency department (ED) a laboratory-automated platform. Methods A total 30 specimens were collected from at our hospital simultaneously tested for urinalysis (UA) on POCT Siemens Clinitek Status+ analyzer using Multistix 10SG strip. In laboratory, we perf...

Background: Despite improvement in sterilization techniques, peri-prosthetic joint infection (PJI) is the most fearsome complication after hip and knee arthroplasties. Various strategies have been devised from time to diagnose treat PJI. Recently, Leukocyte esterase alpha-defensin are identified as markers of active synovial fluid. Therefore, kits designed detect these two during surgery. If fo...

Aims and Objectives: The aims objectives of the study are to find usefulness urine dipstick urinalysis in children with an intention identify parameters which most likely point toward presence urinary tract infection (UTI), whether a combination analyzed rather than single parameter is useful suggesting or absence UTI. Methods: was prospective observational done 401 below 16 years age clinicall...

The control system described here is used to monitor the performance of urinary reagent-strip tests for leukocytes. The presence of leukocyte esterase in the urine is used as a marker for leukocytes in urine. The control system is based on sonicated leukocytes, isolated from whole blood. The esterase activity of this sonicate is determined by spectrophotometry with the N-tosyl-L-alanine ester o...

OBJECTIVES Rapid diagnostic tests can screen out negative samples and can save valuable time and money. The study was conducted to assess the usefulness of leukocyte esterase, nitrate reductase and quantitative microscopic unspun urine wet mount examination in rapidly diagnosing urinary tract infections (UTI). METHODS Four hundred and fifty samples were tested by semi-quantitative culture on ...

The Chemstrip LN (Boehringer Mannheim Biochemicals, Indianapolis, Ind.), designed to detect pyuria and bacteriuria, was compared with culture of 1,020 unselected, consecutive midstream urine specimens and evaluated on its ability to predict colony counts at three levels. At the level of greater than or equal to 10(5) CFU/ml, the combined test (detection of leukocyte esterase and nitrite) had se...