Episodic hypersomnia, compulsive excessive eating and erotic behaviour, with schizophrenic-like mental symptoms are the hallmarks of the rare Kleine-Levin syndrome. This paper traces the origins of its description back to the 18th century and the changing concepts of its complex organic-psychogenic aetiology. The eventual, spontaneous disappearance of the syndrome is unexplained.

The positive correlation seen in the ER, PR scores and Her 2 neu amplification between the primary tumour and lymph node metastases and the absence of a significant difference between the score of ER, PR and the amplification of Her 2 neu between the primary tumour and the lymph node metastases indicates that there is a concordance in these parameters between the primary tumour and its nodal me...