Colonization of the infant gut by microorganisms over the first year of life is crucial for development of a balanced immune response. Early alterations in the gastrointestinal microbiota of neonates has been linked with subsequent development of asthma and atopy in older children. Here we describe high-resolution culture-independent analysis of stool samples from 6-month old infants fed daily ...

We study existence of a restricted least general generalization (LGG) with the property that LGGs of clauses from a pre-fixed set belong to this set. We show that there is no such LGG even in simple sets of clauses such as bounded-size clauses or treewidth-1 clauses.

We have previously reported the purification of a 37-kd platelet-agglutinating protein (PAP p37) from the plasma of a patient with thrombotic thrombocytopenic purpura (TTP) that was shown to be present in a subset of TTP patients. The platelet agglutination induced by PAP p37 has been shown to be inhibited by lgG from normal human adults and the same TTP patient after recovery. To elucidate the...

OBJECTIVE The impact of pregnancy on survival in female patients with low-grade glioma (LGG) is unknown and controversial. The authors designed a retrospective cohort study on prospectively collected registry data to assess the influence of pregnancy and child delivery on the survival of female patients with LGG. METHODS In Norway, the reporting of all births and cancer diagnoses to the Medical...

OBJECTIVE To evaluate the hypoallergenicity of an extensively hydrolysed (EH) casein formula supplemented with Lactobacillus rhamnosus GG (LGG). DESIGN A prospective, randomised, double-blind, placebo-controlled crossover trial. SETTING Two study sites in Italy and The Netherlands. STUDY PARTICIPANTS Children with documented cow's milk allergy were eligible for inclusion in this trial. ...

OBJECTIVE To estimate the cost-effectiveness of using an extensively hydrolyzed casein formula (eHCF) containing the probiotic Lactobacillus rhamnosus GG, (eHCF + LGG; Nutramigen LGG) as first-line management for cow's milk allergy (CMA) compared with eHCF alone, soy-based formulae (SBF), hydrolyzed rice formulae (HRF), and amino acid formulae (AAF) in Italy, from the perspective of the Italian...

BACKGROUND Glioma is a type of tumor that develops in the central nerve system, mainly the brain. Alterations of genomic sequence and sequence segments (such as copy number variations or CNV and copy neutral loss of heterozygosities or cnLOH) are thought to be a major determinant of the tumor grade. METHODS We mapped genomic variations between low-grade and high-grade gliomas (LGG and HGG) in...

ObjectivesTo compare the impact of different formulas on occurrence other atopic manifestations and time immune tolerance acquisition.Study designIn a 36-month prospective cohort study, (eczema, urticaria, asthma, rhinoconjunctivitis) acquisition were comparatively evaluated in immunoglobulin E–mediated children with cow's milk allergy (CMA) treated extensively hydrolyzed casein formula contain...

A high correlation (r 0.85) normally exists between the concentration of albumin and of lgG in cerebrospinal fluid (CSF). The correlation is still better (r = 0.96) if the concentrations of the two proteins are also measured in plasma and the CSF/ plasma ratios compared for albumin and lgG. The scatter diagram for these ratios in persons without disease of the nervous system is most useful as a...

The purpose of this study was to describe the quality of life (QOL) of low-grade glioma (LGG) patients at baseline prior to chemotherapy and through 12 cycles of temozolomide (TMZ) chemotherapy. Patients with histologically confirmed LGG with only prior surgery were given TMZ for 12 cycles. QOL assessments by the Functional Assessment of Cancer Therapy-Brain (FACT-Br) were obtained at baseline ...