We investigated whether 6-gingerol affects the maturation and proliferation of osteoblast-like MG63 cells in vitro. Osteoblast-like MG63 cells were treated with 6-gingerol under control conditions, and experimental inflammation was induced by tumor necrosis factor-α (TNF-α). Expression of different osteogenic markers and cytokines was analyzed by real-time PCR, Western blotting, and enzyme-link...

UNLABELLED Adult bone tissue is continuously being remodelled and bone mass is maintained by a balance between osteoclastic bone resorption and osteoblastic bone formation. Alteration of osteoblastic cell proliferation may account in part for lack of balance between these two processes in bone loss of osteoporosis. There is calcium (Ca2+) control in numerous cellular functions; however, involve...

Semiempirical methods are used to characterize and parametrize the effects of intermediate coupling and configuration interaction on the energy levels of the 3s3p, 3p2 and 3s3d configurations for ions in the Mg isoelectronic sequence. These parametrizations are then used to predict the branching fractions for the 3s3p–3p2 and 3s3p–3s3d transition arrays. The predictions are compared with the MC...

Mishra R, Rao V, Ta R, Shobeiri N, Hill CE. Mg and MgATP-inhibited and Ca /calmodulin-sensitive TRPM7-like current in hepatoma and hepatocytes. Am J Physiol Gastrointest Liver Physiol 297: G687–G694, 2009. First published August 6, 2009; doi:10.1152/ajpgi.90683.2008.—Although understood to be ubiquitously expressed, the functional identification and significance of Mg -inhibited, nonspecific ca...

Jian-Song WU1,∗, Ying-Kai XIAO, Yu-Ping LIU, Wan-Bang XU, Mei-Fang LIANG, Jian CHENG, Jian-Ping WAN, Ling-Zhu CHEN School of Chemistry Science and Technology, Zhanjiang Normal College, 524048, Zhanjiang-CHINA e-mail: [email protected] Key Laboratory of Salt Lake Resources and Chemistry, Qinghai Institute of Salt Lakes, Chinese Academy of Sciences, 810008, Xining-CHINA Guangdong Institute fo...

objective(s) this study planned to assess antidepressant like activity of aqueous extract from leaves of citrus maxima merr. (rutaceae). materials and methods boiling was used for aqueous extraction. acute toxicity study was performed in mice. antidepressant activity was studied using locomotor activity test, modified forced swimming test (fst) and tail suspension test (tst). three doses 100, 2...

depression is a heterogenous, multifaceted disorder with symptoms manifested at the psychological, behavioral and physiological level. therefore, present study was designed as a model to analyze the long lasting effects of methylmercury chloride in male rats with a focus on depression like behavior. male albino rats of wistar strain were exposed orally to a dose of 2 mg/kg of methylmercury chlo...