Probiotics have been found as important elements against reproductive toxicity. So the use of probiotics has increased day by to combat with several disorders related health. In current study, potential role including Lactobacillus casei (L1) and coagulans (L2) demonstrated a tetramic acid-derived pesticide Spirotetramat which cause variable toxicity at different levels in life cycle various or...

A series of pyridazinone derivatives (19-34) were synthesized with an aim to synthesize safer anti-inflammatory agents. The compounds were evaluated for their anti-inflammatory, analgesic, ulcerogenic and lipid peroxidation (LPO) actions. The percentage inhibition in edema at different time intervals indicated that compounds 20, 26, 28 and 34 exhibited good anti-inflammatory potential, comparab...

Two widely used antipsychotic drugs, chlorpromazine (CPZ) and trifluoperazine (TFZ) inhibit NADPH-induced microsomal lipid peroxidation (LPO). Study of microsomal membrane fluidity revealed considerable disorganization in its architecture in the presence of NADPH, which can be restored back in the presence of CPZ and TFZ. NADPH-dependent microsomal LPO is catalyzed by NADPH: cytochrome P450 red...

The follicular fluid environment surrounding the oocytes may play a critical role in fertilization and subsequent embryo development. The goal of our study was to evaluate the oxidative stress markers in the semen, blood serum, and follicular fluid of couples undergoing Intracytoplasmic Sperm Injection (ICSI). Two hundred and eight infertile couples underwent ICSI and the levels of superoxide d...

W e have been studying a novel, reductant-dependent lipid antioxidant system in r a t liver preparations. In a preceding communication we show tha t this is triggered by nucleoside triphosphates, possibly via a G-protein mechanism. I t is selectively antagonised by cromoglycate, a nucleoside diphosphokinase inhibitor. Lipid peroxidation (LPO) was initiated non-enzymatically with 0.2 mM ascorbat...

OBJECTIVE To investigate the effects of fluoride on lipid peroxidation, DNA damage and apoptosis in human embryo hepatocyte L-02 cells. METHODS Lipid peroxide (LPO) level, reduced glutathione (GSH) content, DNA damage, apoptosis, and cell cycle analysis were measured after in vitro cultured L-02 cells were exposed to sodium fluoride at different doses (40 microg/mL, 80 microg/mL, and 160 micr...

The aim of this study is to assess the effect polyphenol curcumin on lipid peroxidation (LPO) in homogenate cerebral hemispheres from rats exposed round-the-clock lighting (RCL) and kept high-calorie carbohydrate-lipid diet (HCCLD). experiments were performed 21 white male Wistar weighing 210-250 g, divided into 3 groups 7 animals each. Animals group 1 (control I) a standard vivarium equal alte...

Lipid peroxidation (LPO), an oxidative chain reaction often occurring in the human body and food, is harmful to health. Due its convenience low cost, this guideline highlights benefits drawbacks of LPO models by spectrophotometer vitro vivo. The preparation process mechanism lipid substrates, oxidation triggers detection methods are discussed paper better screen antioxidants. substrates mostly ...