Phytocompounds have been used in medicine for decades owing to their potential in anti-inflammatory applications. However, major difficulties in achieving sustained delivery of phyto-based drugs are related to their low solubility and cell penetration, and high instability. To overcome these disadvantages, nanosized delivery technologies are currently in use for sustained and enhanced delivery ...

Efficient drug delivery is essential for many therapeutic applications. In this context, Trojan peptoids have attracted attention as powerful tools to deliver bioactive molecules into living cells. Certain cell-penetrating peptides, peptide mimetics, and peptoids have been shown to be endowed with a transport function and the structural features of this function have been characterized. However...

Ethosomes are noninvasive delivery carriers that enable drugs to reach the deep skin layers and the systemic circulation. Although ethosomal systems are conceptually sophisticated, they are simple in their preparation, safe for use a combination that can highly expand their application. Ethosomes are soft, malleable vesicles tailored for enhanced delivery of active agents. Because of their uniq...

Egg albumin nanoparticles (EANPs) are considered safe, economic and biocompatible drug carrier systems to carry out effective targeted delivery. EANPs have low-cost and safe nanomaterials to carry out more improved drug loading capacity for loaded bioactive molecules with high site specificity and low cytotoxicity and desired delivery rate. Size controlling of EANPs was carried out by using imp...

Abstract Nutraceuticals have recently gained interest owing to their valuable contribution in the treatment of several diseases, with high safety margin and low incidence side effects. However, efficacy is limited by some challenges, namely poor solubility, permeability, and, consequently, bioavailability. Delivery carriers proven that they can overcome almost all aforementioned limitations, le...

The impact of bone diseases and trauma in the whole world has increased significantly in the past decades. Bioactive glasses are regarded as an important bone regeneration material owing to their generally excellent osteoconductivity and osteostimulativity. A new class of bioactive glass, referred to as mesoporous bioglass (MBG), was developed 7 years ago, which possess a highly ordered mesopor...

Polymers have always been valuable excipients in conventional dosage forms, also have shown excellent performance into the parenteral arena, and are now capable of offering advanced and sophisticated functions such as controlled drug release and drug targeting. Advances in polymer science have led to the development of several novel drug delivery systems. Interpenetrating polymer networks (IPNs...

Objective(s): Development of an oral sustained-controlled release vehicle which, slowly releases the drug and maintains an effective drug concentration for a long time is aimed.Materials and Methods: A biodegradable magnetic polymeric drug delivery vehicle, using superparamagnetic iron oxide nanoparticles encapsulating by polyvinylpyrrolidone-block-polyethylene glycol-block-poly methacrylic aci...