It is becoming evident that lncRNAs may be an important class of pervasive genes involved in carcinogenesis and metastasis. However, the biological and molecular mechanisms of lncRNAs in retroperitoneal liposarcoma have never been reported. In our study, we found a novel lncRNA PILRLS (Proliferation Interacting LncRNA in Retroperitoneal Liposarcoma), which as an oncogene significantly overexpre...

Primary liposarcoma of the mediastinum is an uncommon tumour. We report a case of a 45-year-old female who was found incidentally to have a large anterior mediastinal mass. Complete removal of the tumour was accomplished successfully. Appropriate immunohistochimical stains were performed, confirming the presence of a well-differentiated liposarcoma of the mediastinum. We describe an unusual cas...

INTRODUCTION Liposarcoma is rare in the mediastinum and is less than 1% of all mediastinal tumors. In the present report, we demonstrated our case and summarized the principal treatment of the mediastinal liposarcoma with literature review. PRESENTATION OF CASE A 50-year-old man presented at our hospital with complain of dyspnea. Chest radiography showed remarkable cardiomegaly. Computed tomo...

BACKGROUND Primary colonic and dedifferentiated liposarcomas are both remarkably rare. This work describes a case of primary colonic well-differentiated/dedifferentiated liposarcoma and reviews the clinical characteristics and current therapies for liposarcoma tumors. CASE PRESENTATION A 52-year-old woman was referred to our hospital with a submucosal tumor of the ascending colon. Clinical an...

The q13 to q15 region of human chromosome 12 is frequently and consistently rearranged in malignant and benign adipose tissue tumors as well as benign tumors of smooth muscle and salivary glands. A reciprocal translocation, (12;16) (q13;p11), is characteristic of the myxoid subtype of liposarcoma, whereas translocations within 12q13-14 are frequently observed in benign lipomas. We are using pul...

Download pose: Myxoid liposarcoma is a common subtype of liposarcoma. It is associated in more than 90% es with the chromosomal translocation t(12;16)(q13;p11) leading to the fusion FUS-CHOP gene responsible for the oncogenic transformation of preadipocytes. Recently the marine natural prodbectedin has shown highly selective activity for myxoid liposarcoma, even in the most aggressive -cell sub...

Downloa pose: Myxoid liposarcoma is a common subtype of liposarcoma. It is associated in more than 90% es with the chromosomal translocation t(12;16)(q13;p11) leading to the fusion FUS-CHOP gene responsible for the oncogenic transformation of preadipocytes. Recently the marine natural prodbectedin has shown highly selective activity for myxoid liposarcoma, even in the most aggressive -cell subt...

OBJECTIVE The relative utility of various preoperative diagnostic imaging modalities, including PET (utilizing FDG and FMT), CT, and MR imaging, for evaluation of lipoma and liposarcoma, especially well-differentiated liposarcoma, was investigated. METHODS Imaging findings in 32 patients with histopathologically documented lipoma, including one with fibrolipoma and one with angiolipoma, and 2...

Well differentiated liposarcoma (WDLS) is the commonest subtype of liposarcoma. Recognised subtypes of WDLSs are lipoma-like, sclerosing, spindle cell and inflammatory. The inflammatory variant of WDLS also known as "lymphocyte-rich liposarcoma" is rare. We present a case of inflammatory WDLS occurring in the retroperitoneum, in a patient with a past history of non-Hodgkin lymphoma. We outline ...