An efficient strategy for the preparation of N-linked glycopeptides is described. The method relies on the use of side chain protecting groups on aspartic acid residues, namely the allyl and Dmab esters, which are orthogonal to those utilised in Fmoc-strategy SPPS. After peptide assembly these protecting groups were selectively removed and the resulting free side chains derivatised with a glyco...

CD69 is a transmembrane lectin that can be expressed on most hematopoietic cells. In monocytes, it has been functionally linked to the 5-lipoxygenase pathway in which the leukotrienes, a class of highly potent inflammatory mediators, are produced. However, regarding CD69 gene expression and its regulatory mechanisms in monocytes, only scarce data are available. Here, we report that CD69 mRNA ex...

Nickel-catalyzed intermolecular benzylation and heterobenzylation of unactivated alkenes to provide functionalized allylbenzene derivatives are described. A wide range of both the benzyl chloride and alkene coupling partners are tolerated. In contrast to analogous palladium-catalyzed variants of this process, all reactions described herein employ electronically unbiased aliphatic olefins (inclu...

Abstract Surface analysis of 2-mercaptobenzothiazole (MBTH) adsorbed on brass from 3 wt.% NaCl solution was performed by means X-ray photoelectron spectroscopy and tandem (MS/MS) time-of-flight secondary ion mass spectrometry (ToF-SIMS). These surface analytical techniques were used in association with the gas cluster beam (GCIB) sputtering method at various acceleration energies sizes, which s...

A simple spectrophotometric method is reported her for the estimation of reserpine in polyherbal formulations. Estimation is based on the reaction with3-methylbenzolinone-2hydrazone (MBTH) reagent in presence of cerric ammonium sulphate to yield a violet coloured chromogen, which exhibits and absorption maxima at 580 nm. The chromogen is stable for 10 minutes.

It was theoretically predicted that electric field intensities generated by surface plasmon resonance (SPR) around plasmonic metallic nanostructures could be reduced after covered wide bandgap semiconductor, thus worsening the SPR-mediated photocatalytic activities. However, we found Ag nanocubes (Ag NCs) AgCl demonstrated an abnormal catalytic enhancement. Herein PATP-to-DMAB oxidization used ...

We attempt to provide experimental and theoretical evidence that information of chemical reaction can propagate with plasmonic waveguide along the nanowire and be detected at the remote terminal of nanowire, where the chemical reaction is the surface catalyzed reaction of DMAB produced from PATP assisted by surface plasmon polaritons.