objective(s) a sensitive liquid chromatographic method for the analysis of clarithromycin- a macrolide antibiotic- in human serum, using pre-column derivatization with 9-fluorenylmethyl chloroformate (fmoc-cl) is described. materials and methods the method involved liquid-liquid extraction of the drug and an internal standard (amantadine) followed by pre-column derivatization of the analytes wi...

the aim of this study was to develop an easy analytical method for determining flam prop-m- iso propyl residues in honey by high performance liquid chromatography with uv detection (hplc/uv) for routine analysis. chromatographic separation was carried out at room temperature on a zorbax eclipse xdb- c18, 100 å pore size, 5 μm particle size (300 mm × 3 mm i.d.) column using a mobile phase of met...

Abstract A novel basic ionic liquid based on imidazolium cation is designed, synthesized and successfully used as a catalyst for the one-pot synthesis of 4-Oxo-6-aryl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile derivatives. The remarkable features of this new catalyst are its ethyleneoxy bridge which participates in dissolving organic compound in the ionic liquid and its strong base co...