Dietary necrotic liver degeneration is recognized now as a distinct disease entity; it is a deficiency of complex nature, which, so far, has been produced in rats (2, 3), mice (4), rabbits,’ and pigs (5, 6). The disease in rats is primarily characterized by acute massive necrosis of the liver which develops suddenly after an uneventful experimental period of several weeks duration. In most anim...

An abscess of the round ligament liver in children, as a result an inflammatory process, often leading to necrosis, is extremely rare occurrence. Formations must be differentiated from tumors, which can diagnosed using instrumental research methods. In available literature on liver, authors speak about preference for complete excision ligament. However, analyzing experience (5 clinical examples...

Bond, E. J., Butler, W. H., de Matteis, F., and Barnes, J. M. (1968). Brit. J. industr. Med., 26, 335-337. Effects of carbon disulphide on the liver of rats. Normal rats surviving a single oral dose of carbon disulphide (CS2) show liver enlargement and depression of drug-metabolizing enzymes but no liver necrosis. If the drug-metabolizing enzymes are stimulated by phenobarbitone before exposure...

objective(s): the objective of this study was to investigate the hepatoprotective effect of licochalcone b (lcb) in a mice model of carbon tetrachloride (ccl4)-induced liver toxicity. materials and methods: hepatotoxicity was induced in mice by a single subcutaneous injection (sc) of ccl4. the lcb was administered orally once a day for seven days (po) as pretreatment at three doses of 1, 5, and...

The histopathological effects of Linear Alkylbenzene Sulfonate on the gill, liver and kidney tissues of the Caspian kutum, Rutilus frisii kutum were studied. The fish were exposed to three sublethal concentrations of anionic detergent, Linear Alkylbenzene Sulfonate (LAS) for short term intervals (192 h). Gill, liver and kidney samples were collected after 192 h of exposure to LAS and lesions we...

Acetaminophen (APAP) overdose is the most frequent cause of acute liver failure in the US and many western countries. It is well known that APAP induces mitochondrial damage to trigger centrilobular necrosis. Emerging evidence suggests that autophagic removal of damaged mitochondria may protect against APAP-induced liver injury. Electron and confocal microscopy analysis of liver tissues reveale...

Two hundred and one days old, unsex broilers were used in the current study to investigate potential of irradiated chitosan for improving histological liver, included condition activities liver cells biochemical. Chitosan isolated from shrimp chitin using a chemical technique. The sample broiler assigned four groups, with five replication each treatment group consisted fifty broilers. There tre...

Excessive use of pesticides has led to increasing concern about undesirable effects on human health and the environment. Imidacloprid is an internationally used neonicotinoid insecticide due its significant toxicity insects. Its residues may reach food chain, which important for examining potentially harmful properties imidacloprid exposure. The current study aimed characterize histopathologica...

hepatic ischemia-reperfusion (i/r) is a common phenomenon during liver surgery, transplantation, infection and trauma which results in damage and necrosis of the hepatic tissue through different pathways. mechanisms involved in i/r damage are very intricate and cover several aspects. several factors are involved in i/r-induced damages; briefly, decrease in sinusoidal perfusion and atp generatio...