Transplant oncology is a relatively new field in which transplantation used to treat patients who would otherwise be unresectable. New anticancer treatment paradigms using tumor and transplant immunology cancer immunogenomics are emerging. In turn, liver (LT) has become potential therapy for certain with colorectal (CRC) metastasis, hepatocellular (HCC), cholangiocarcinoma (CCA), metastatic neu...

BACKGROUND End-stage liver disease (ESLD) is the most common cause of secondary immunoglobulin A nephropathy (IgAN). Multiple mechanisms have been proposed to explain the association between liver disease and IgAN. Although some mechanisms are expected to reverse in patients after liver transplant, the long-term renal prognosis is unclear for these patients. METHODS This observational retrosp...

Immune senescence is the normal process whereby the human immune system ages, but becomes less effective. We investigated whether liver transplant recipients have features of immune senescence. Lymphocytes from 97 liver transplant recipients with established grafts and 41 age-matched and sex-matched controls were subjected to an 8-color flow cytometry assay that measured expression of killer ce...

background hepatitis c virus (hcv) infection still exists as a health concern among the transplant patients. because of the severity of the disease, different responses to treatment, and side effects resulting from long therapeutic period, determination of genotypes and viral loads can help choose the best treatment protocols. objectives this study aimed to determine the hcv genotypes and its d...

Liver transplantation has indeed evolved from an experimental procedure in the early 1980s to the most effective treatment for patients with advanced liver cirrhosis and for selected patients with hepatocellular carcinoma and fulminant hepatic failure. In this new scenario, the transplant hepatologist plays a crucial clinical role, with essential duties and skills to manage the complexities enc...

Background: Progressive familial intrahepatic cholestasis is a disease presenting with severe and progressing to the end-stage liver later. Liver transplantation treatment modality available for progressive cholestasis, especially in patients or those who are unsuitable have failed biliary diversion. Objectives: To evaluate clinical pathological characteristics of had undergone determine post-t...

Background: Orthotopic liver transplant (OLT) is an established life saving procedure for both acute and chronic liver failure. A number of malignancies have been reported in liver transplant recipients over the past thirty years.

Acute kidney injury (AKI) and chronic kidney disease (CKD) are common in patients awaiting liver transplantation, and both have a marked impact on the perioperative and long-term morbidity and mortality of liver transplant recipients. Consequently, we reviewed the epidemiology of AKI and CKD in patients with end-stage liver disease, highlighted strategies to prevent and manage AKI, evaluated th...

Enterococcus faecalis is a leading cause of infections in liver transplant patients. This study reviewed the incidence of virulence factors such as hemolysin, gelatinase, aggregation substances (asa1 and asa373), or the enterococcal surface protein (Esp) in isolates from liver transplant patients. In total, 133 isolates from liver transplant patients were compared with 47 isolates from feces of...

OBJECTIVES Neurologic complications are common after kidney and liver transplant. Neurologic complications affect mortality and morbidity in transplant recipients, and neuropathic pain is an important symptom affecting a patient's quality of life. The aim of the present study was to provide readers with our experience regarding causes and treatment of neuropathic pain in patients undergoing kid...