Profound analgesia or pain control with local anesthetics is essential for most dental procedures in endodontic and restorative treatments, tooth extraction and minor oral surgery. However, dental clinicians frequently experience that it is difficult for infiltration and nerve block injections to achieve clinically acceptable local anesthesia in the presence of pupil and periapical inflammation...

Occipital neuralgia is a form of headache that involves the posterior occiput in the greater or lesser occipital nerve distribution. Pain can be severe and persistent with conservative treatment. We present a case of intractable occipital neuralgia that conventional therapeutic modalities failed to ameliorate. We speculate that, in this case, the cause of headache could be the greater occipital...

BACKGROUND Analgesic discography (discoblock) can be used to diagnose or treat discogenic low back pain by injecting a small amount of local anesthetics. However, recent in vitro studies have revealed cytotoxic effects of local anesthetics on intervertebral disc (IVD) cells. Here we aimed to investigate the deteriorative effects of lidocaine and bupivacaine on rabbit IVDs using an organotypic c...

Introdouction: Injection of local anesthesia during dental procedures can induce metabolic changes. The purpose of this study was to evaluate the changes in the serum blood glucose levels after the injection of lidocaine with a vasoconstrictor during tooth extraction. Materials and methods: In this clinical trial study, we enrolled 60 patients. We extracted mandibular teeth by using inferior al...

INTRODUCTION Failure to achieve adequate and profound anesthesia in teeth with acute pulp inflammation is a common condition during emergency visits in root canal therapy. Many different anesthetic solutions such as morphine and capsaicin have accordingly been examined. Mannitol- an alcoholic sugar with high osmotic pressure level- is applicated for reducing intracranial and post retinal pressu...

Dermatologic surgeons have long been trying to find ways to eliminate patient discomfort associated with dermatologic procedures. Although some dermatologic procedures, such as facial resurfacing and extensive procedures performed on children, require intravenous or general anesthesia, dermatologic surgical procedures usually require only local anesthesia, which is frequently administered via i...

BACKGROUND Idiopathic adhesive capsulitis is a condition of uncertain etiology characterized by pain and decreased shoulder range of motion (ROM) that occurs without a known intrinsic disorder. Many treatments have been advocated, yet the best option remains unclear. The purpose of this study was to determine if arthrographic injection of the shoulder joint with steroid and local anesthetic res...

BACKGROUND Dentists administer thousands of local anesthetic injections every day with few reports of serious complications. However, misjudging the anatomy involved during local anesthetic administration can result not only in inadequate or incomplete anesthesia, but in other complications such as paresthesia, bleeding or hematoma formation, or in serious systemic complications. OVERVIEW The...

Purpose. The aim of this study was to evaluate the effect of adhesiolysis followed by the injection of steroid and local anesthetic during epiduroscopy on sensory nerve function, pain and functional disability in patients with chronic sciatica. Methods. Epidural adhesiolysis using epiduroscopy followed by the injection of steroid and local anesthetic were scheduled in 19 patients with chronic s...

BACKGROUND AND OBJECTIVES Perineural dexamethasone prolongs the duration of single-injection peripheral nerve block when added to the local anesthetic solution. Postulated systemic mechanisms of action along with theoretical safety concerns have prompted the investigation of intravenous dexamethasone as an alternative, with decidedly mixed results. We aimed to confirm that addition of intraveno...