The Flexible Job Shop Scheduling Problem (FJSP) is one of the most general and difficult of all traditional scheduling problems. The Flexible Job Shop Problem (FJSP) is an extension of the classical job shop scheduling problem which allows an operation to be processed by any machine from a given set. The problem is to assign each operation to a machine and to order the operations on the machine...

All modes of cell migration require rapid rearrangements of cell shape, allowing the cell to navigate within narrow spaces in an extracellular matrix. Thus, a highly flexible membrane and a dynamic cytoskeleton are crucial for rapid cell migration. Cytoskeleton dynamics and tension also play instrumental roles in the formation of different specialized cell membrane protrusions, viz. lamellipodi...

With respect to the membrane lipid theory as a molecular mechanism for local anesthetics, two critical subjects, the negligible effects of charged drugs when applied extracellularly and the stereoselective effects of enantiomers, were verified by paying particular attention to membrane components, phospholipids with the anionic property, and cholesterol with several chiral carbons. The membrane...

Biomimetic membranes that contain several molecular components are studied theoretically. In contact with another surface, such as a solid substrate or another membrane, some of these intramembrane components are attracted by the second surface and, thus, act as local stickers. The cooperative behavior of these systems is characterized by the interplay of (i) attractive binding energies, (ii) e...