CONCLUSION It was proved that cyclin D1-positive status in surgical margins was an independent prognostic indicator of local recurrence. The expression of cyclin D1 in tumor-free surgical margins may better predict local recurrence in patients with head and neck squamous cell carcinoma (HNSCC) after surgical treatment with curative intent. OBJECTIVE This retrospective study aimed to determine...

granular cell tumor (gct) was first described by abrikossoff in 1926. gct is a rarely seen soft tissue tumor and is generally benign. while the tumor can be seen in all parts of the body it is generally located on the head and neck region, and especially on the tongue. gct is rarely seen in the anal-perianal region. in accordance with literature this case was reported because it was thought to ...

OBJECTIVE To describe the cytologic transformation and tumor progression in a series of uveal melanomas. METHODS Fifteen cases of uveal melanoma, treated by primary transscleral local resection without primary adjuvant treatment, needed enucleation because of local tumor recurrence. Cytologic and cell morphometric features of the primary tumor and the intraocular recurrence were compared, wit...

Studies have shown that bone marrow-derived cells play an important role in tumor recurrence after chemotherapy and radiotherapy. In this study, we examined the relationship between the accumulation of Gr-1+CD11b+ cells and tumor recurrence after irradiation in tumor-bearing mice. By transplanting bone marrow cells into whole body-irradiated mice depleted of bone marrow, we assessed the role of...

BACKGROUND Conservative surgery can be regarded as the standard treatment for most early stage breast tumors. However, a minority of patients treated with conservative surgery will present local or locoregional recurrence. Therefore, it is of interest to evaluate the possible factors associated with this recurrence. METHODS A population-based retrospective study using data from the Tumor Regi...

OBJECTIVE To evaluate outcomes of radical excision of feline injection-site sarcomas (ISS) via assessment of local recurrence and metastasis rates, survival times, and complications associated with surgery. DESIGN Retrospective case series. ANIMALS 91 cats with ISS. PROCEDURES Medical records of cats that had radical excision of ISS without adjunctive treatment were reviewed. Information ...

PURPOSE To evaluate the patterns, the risk factors, and the management of recurrence following brachytherapy in patients with posterior uveal melanoma, given that an understanding of the recurrence patterns can improve early recognition and management of local treatment failure in such patients. DESIGN Retrospective cohort study. METHODS Setting: Multispecialty tertiary care center. PARTI...

Background and Objectives: To investigate critical prognostic factors for local recurrence in patients with rectal adenocarcinoma. Methods: We enrolled 221 consecutive patients who had histologically confirmed adenocarcinoma of the rectum and underwent surgery in our hospital between January 2000 and December 2014. Total mesorectal excision was performed in all patients undergoing a sphincter-s...