نتایج جستجو برای: losartan potassium

تعداد نتایج: 80989  

Journal: :International Journal of Health Sciences (IJHS) 2022

Microemulsions are the advanced form of conventionally used emulsions, which is a biphasic dosage consisting two immiscible liquids that brought together with application surfactants and cosurfactants. The micron sized globules microemulsions helps in achieving targeted action improved availability stability. studies related to concluded its potential delivering various hydrophilic lipophilic d...

2012
Satyabrata Bhanja Malla Reddy

Losartan potassium is an angiotention receptor antagonist, used in the management of hypertension. The objective of the proposed research work is to prepare and evaluate the mouth dissolving/disintegrating tablets (MDTs) of losartan Potassium, which avoid the first-pass metabolism, improved the dissolution rate and enhance the bioavailability. Mouth dissolving tablets (MDTs) were prepared by di...

2005
Ibrahim A. Darwish

Studies were carried out, for the first time, to investigate the charge-transfer reactions of losartan potassium (LOS-K) as n-electron donor with the -acceptor iodine and various -acceptors: 7,7,8,8-tetracyanoquinodimethane, 1,3,5-trinitrobenzene, 2,3-dichloro-5,6-dicyano1,4-benzoquinone, p-chloranilic acid, tetracyanoethylene, 2,3,5,6-tetrabromo-1,4-benzoquinone, 2,3,5,6-tetrachloro-1,4-benzoq...

2010
Frederik Persson Julia B. Lewis Edmund J. Lewis Peter Rossing Norman K. Hollenberg Hans-Henrik Parving

OBJECTIVE Proteinuric diabetic patients with reduced glomerular filtration rate (GFR) are at high risk of renal and cardiovascular disease progression and treatment-related adverse events. This post hoc analysis assessed the efficacy and safety of aliskiren added to the maximal recommended dose of losartan according to baseline estimated GFR (eGFR) (stage 1-3 chronic kidney disease [CKD]). RE...

2012
T. S. KEERTHI S. K. SENTHIL KUMAR

Present investigation describes preparation of microspheres by solvent evaporation followed by in vitro characterization of microspheres to evaluate the effect of method of preparation on physical properties and drug release profile of microspheres. The microspheres were found to be discrete, spherical with free flowing properties. The morphology (Scanning Electron Microscopy), particle size di...

Journal: :Journal of hypertension 2016
Flávio D Fuchs Luiz César N Scala José F Vilela-Martin Renato Bandeira de Mello Francisca Mosele Paul K Whelton Carlos E Poli-de-Figueiredo Paulo Ricardo de Alencastro Ricardo Pereira E Silva Miguel Gus Luiz Aparecido Bortolotto Rosane Schlatter Evandro José Cesarino Iran Castro José A Figueiredo Neto Hilton Chaves André Avelino Steffens João Guilherme Alves Andréa Araujo Brandão Marcos R de Sousa Paulo Cesar Jardim Leila B Moreira Roberto Silva Franco Marco Mota Gomes Abrahão Afiune Neto Felipe Costa Fuchs Dario C Sobral Filho Antônio C Nóbrega Fernando Nobre Otávio Berwanger Sandra C Fuchs

OBJECTIVES To compare the blood pressure (BP)-lowering efficacy of a chlorthalidone/amiloride combination pill with losartan, during initial management of stage I hypertension. METHODS In a randomized, double-blind, controlled trial, 655 participants were followed for 18 months in 21 Brazilian academic centers. Trial participants were adult volunteers aged 30-70 years with stage I hypertensio...

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