Macrophages tightly control the production and clearance of red blood cells (RBC). During steady state hematopoiesis, approximately 10(10) RBC are produced per hour within erythroblastic islands in humans. In these erythroblastic islands, resident bone marrow macrophages provide erythroblasts with interactions that are essential for erythroid development. New evidence suggests that not only und...

By far the sexiest piece of software associated with ASR is the large-vocabulary decoder. Since this course is nothing if not about being sexy, this assignment will deal with various aspects of large-vocabulary decoding. In the first portions of this lab, we will investigate the various steps involved in building static decoding graphs as will be needed by our decoder. In the second half of the...

Functional neuroimaging studies have noted that brain regions supporting theory of mind (ToM) overlap remarkably with those underlying episodic memory, suggesting a link between the two processes. The present study shows that memory for others' past experiences modulates significantly our appraisal of, and reaction to, what is happening to them currently. Participants read the life story of two...

L ipopolysaccharide (LPS) is a major component of the outer membrane of Gram-negative bacteria. LPS is one of the most potent microbial inducers of inflammation and is responsible for many of the deleterious effects of pulmonary infections. In contrast, surfaces of the body are constantly exposed to small amounts of LPS. This interaction appears to stimulate more beneficial, protective mechanis...