نتایج جستجو برای: low density lipoprotein

تعداد نتایج: 1525937  

2013
Uday Saxena Michael G. Klein Teresa M. Vanni J. Goldberg

Lipoprotein lipase (LPL), the rate-limiting enzyme for hydrolysis of plasma lipoprotein triglycerides, is a normal constituent of the arterial wall. We explored whether LPL affects (a) lipoprotein transport across bovine aortic endothelial cells or (b) lipoprotein binding to subendothelial cell matrix (retention). When bovine milk LPL was added to endothelial cell monolayers before addition of ...

Journal: :The Journal of biological chemistry 1980
S Gatt E L Bierman

Cultured human skin fibroblasts incubated at 37 degrees C with sonically dispersed, positively charged liposomes containing sphingomyelin internalized and metabolized the phospholipid. Sphingomyelin incorporation into the cells produced a reduction in low density lipoprotein binding and degradation. Lecithin-containing liposomes were much less effective. In addition, incubation with sphingomyel...

Objective(s): Hypercholesterolemia is a common metabolic disorder in developing and developed countries and is associated with the increased rates of chronic kidney disease (CKD). Statin therapy could reduce cholesterol synthesis as well as progression of CKD. Diversity between statins causes variety in pharmacokinetics and pharmacodynamics and also their pleiotropic e...

Journal: :avicenna journal of medical biochemistry 0
siamak shahidi neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran; neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran. tel: +98-8138380462, fax: +98-8138380208 zahra jabbarpour department of physiology, school of medicine, hamadan university of medical sciences, hamadan, ir iran masoud saidijam research center for molecular medicine, hamadan university of medical sciences, hamadan, ir iran rasoul esmaeili department of physiology, school of medicine, hamadan university of medical sciences, hamadan, ir iran alireza komaki neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran nasrin hashemi firouzi neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran

conclusions it can be concluded that tempol can improve dyslipidemia and may decrease hyperglycemia in diabetes. it seems that antioxidants such as tempol can improve dyslipidemia and may decrease hyperglycemia in diabetes. results the blood glucose level increased following diabetes induction. the level of blood glucose in the diabetic receiving tempol group decreased compared to the control d...

   لیپوپروتئین‌ها ساختارهای مدوری هستند که وظیفه انتقال لیپیدهای هیدروفوبیک (تری‌گلیسرید TG و کلسترول استریفیه EC) را در جریان خون به‌عهده دارند. این ذرات داری یک پوسته متشکل از فسفولیپید، کلسترول آزاد (FC) و پروتئین‌ها (اصطلاحاً آپولیپوپروتئین یا آپوپروتئین) هستند که حول یک بخش مرکزی حاوی TG و EC را پوشانده‌اند. لیپوپروتئین‌ها را بر مبنای روش جداسازی در آزمایشگاه‌ها طبقه‌بندی کرده‌اند. در این خ...

Journal: Physical Treatments 2020

Purpose: Several studies have been done on the effects of fasting on human health indicating the beneficial effects of fasting on weight control, lipid metabolism, and lowering blood pressure in healthy people. The present study aimed at investigating the effects of Ramadan fasting on apolipoproteins A and B (apo A and B) and the atherogenic index of the fasting and non-fasting students. Metho...

Mohammad Ali Ghaffari, Taibeh Ghiasvand,

Background: A great deal of evidence has indicated that oxidatively modified LDL plays a critical role in the initiation and progression of atherosclerosis. Antioxidants that can prevent LDL oxidation may act as antiatherogens. Copper is a candidate for oxidizing LDL in atherosclerotic lesions. The binding of copper ions to LDL is usually thought to be a prerequisite for LDL oxidation by copper...

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