Purpose: Allometry is a method to express the relationship between physiological and anatomical variables. It can be used to measure the vital capacity through mathematical equations. This study aimed at evaluating lung function indices to estimate the maximal aerobic power by respiratory gas analysis device and the allometric equation. Methods: This study was a descriptive and correlational r...

The degree of lung distension during quiet respiration, the so-called respiratory position or resting expiratory level, is essentially determined by a balance between the passive forces produced by the thoracic wall and the active forces due to the elastic properties of the lung. Therefore the interplay of these forces has a direct role in determining the extent of the functional residual capac...

Previous studies have shown that long-lived memory CD8(+) T cells persist in the lung airways following the resolution of a murine Sendai virus infection. These cells are CD11a(low), noncytolytic, and do not proliferate in the lung airways raising the possibility that they are "end stage" or terminally differentiated memory cells. In this current report, we investigated the functional character...

   Cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. However, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma.    The purpose of this study was to determine the extent of change...

OBJECTIVES To evaluate the use of specific compliance (static compliance/functional residual capacity) to adjust mean airway pressure, resulting in optimal gas exchange during high-frequency oscillatory ventilation in a surfactant-deficient newborn piglet. DESIGN Prospective controlled animal study. SETTING Laboratory. SUBJECTS Eight newborn piglets at 5 days of age. BACKGROUND High-fre...

The effect of positive expiratory pressure breathing, alone and in combination with coughing, was investigated in eight patients with cystic fibrosis. Functional residual capacity and total lung capacity was measured with a body plethysmograph before, during, and immediately after breathing with expiratory pressure of 5 and 15 cm H2O, and after a coughing period. The positive expiratory pressur...

Background: The present study aimed to evaluate the effects of different concentrations of cerium oxide nanoparticles (CONPs) on the oxidative stress (OS) status in kidney, lung, and serum of rats. Methods: Male Wistar Rats were treated intraperitoneally with 15, 30, and 60 mg/kg/day of CONPs. The biochemical parameters, including total antioxidant capacity (TAC), total thiol group (TTG), malon...

Abnormalities of lung function in 92 children with idiopathic or congenital scoliosis are described. The changes are restrictive in type with reduction in vital capacity and total lung capacity but normal residual volume. In children whose curves had an early onset, the amount by which vital capacity was reduced depended on the severity of the deformity; in those whose curves began in adolescen...

objective (s): there is corroborating evidence to substantiate redox imbalance and oxidative stress in sepsis that finally leads to organ damage or even death. gamma oryzanol (go) is one of the major bioactive components in rice bran has been considered to function as an antioxidant. the present study was carried out to evaluate the antioxidant activity of gamma oryzanol in vitro and its effica...

BACKGROUND Recent studies described a progressive decline in lung volumes in adult bronchiectasis. Interstitial lung disease is also a feature of bronchiectasis, but whether this is associated with a decline in lung diffusing capacity (measured as the diffusing capacity of the lung for carbon monoxide [D(LCO)]) is not well known. OBJECTIVE To assess longitudinal decline in diffusing capacity ...