OBJECTIVES In our study, we aimed to investigate the anti-inflammatory mediator effects of budesonide (BS), an inhaled corticosteroid and interleukin-10 (IL-10) on a pulmonary contusion in an experimental rat model in which an isolated bilateral pulmonary contusion was created by blunt thoracic trauma. METHODS Fifty-five male Sprague-Dawley rats were used in the study. Sham, control, BS and I...

BACKGROUND Literature concerning lung ultrasonography is largely growing and opening new diagnostic opportunities. The clinical value of the ultrasonographic interstitio-alveolar syndrome, based on artifactual (lung comets or B-lines) rather than real images, in the detection of lung contusion, pneumonia and pulmonary edema, is clearly demonstrated. As clinical echographists, though, we are liv...

Cardiac contusion is an infrequent but occasionally serious complication of deceleration injury. According to ATLS teaching, the true diagnosis of contusion can only be established by direct inspection of the myocardium. The clinically important sequelae of myocardial contusion are hypotension and arrhythmia. Despite recent advances in investigative techniques, myocardial trauma remains an impo...

Traumatic brain injury (TBI) is an important cause of death with a significant worldwide percentage. In the United States, there are approximately 2.8 million TBIs yearly 250,000 hospitalized patients and 50,000 TBI-related deaths. Every year, one hospitalizations in European Union, resulting more than deaths, most which occur due to road traffic accidents. Needless say, these estimations varie...

Spinal cord injury (SCI) causes chronic pain in 65% of individuals. Unfortunately, current pain management is inadequate for many SCI patients. Rodent models could help identify how SCI pain develops, explore new treatment strategies, and reveal whether acute post-SCI morphine worsens chronic pain. However, few studies explore or compare SCI-elicited neuropathic pain in rats. Here, we sought to...

[Purpose] The objective of the study was to compare the incidence, diagnosis, treatment, and prognosis of patients with spinal cord stab injury to those with the more common spinal cord contusion injury. [Subjects] Of patients hospitalized in China Rehabilitation Research Center from 1994 to 2014, 40 of those having a spinal cord stab injury and 50 with spinal cord contusion were selected. [Met...

This study explored the effect of focal cerebral contusion on the expression of ApoE and S-100, and its significance in determining the time of brain injury. Based on a rat model of cerebral contusion, immunohistochemistry was used to analyze the expressions of S-100 and ApoE at different time points after injury. Thirty minutes following cerebral contusion, ApoE protein expression was signific...

A 69-year-old man was admitted to our hospital with cardiopulmonary arrest. Percutaneous cardio-pulmonary support (PCPS) using the right femoral artery and vein was initiated, because ventricular fibrillation continued. Although we succeeded in defibrillation after percutaneous coronary intervention (PCI), a chest radiograph indicated a pneumothorax in the right lung and a pulmonic contusion in...

Background: Chest X-Ray (CXR) is routinely used as the primary diagnostic technique in chest trauma but some possibly life-threatening injuries are repeatedly missed on CXR. Non contrast computed tomography (NCCT) scan a superior device blunt chest. Aim: To compare efficacy of x-ray versus NCCT diagnosis Methodology: The present cross sectional study was performed admitted patients causality Su...

CHEST WALL If a segment of chest wall becomes unstable (e.g. due to multiple rib fractures), particularly when associated with lung contusion, it may be impossible to sustain adequate ventilation (see Chapter 10). Similarly, if the thorax is deformed (e.g. due to kyphoscoliosis), lung expansion will be impaired. These patients may eventually develop ventilatory failure and are prone to recurren...