background and objective: candidiasis is a common opportunistic infection in hiv-infected patients. the spectrum of candida infection is diverse, starting from asymptomatic colonization to pathogenicforms. the low absolute cd4+ t-lymphocyte count has traditionally been cited as the greatest risk factor for the development of oropharyngeal candidiasis and current guidelines suggest increased ris...

Superoxide dismutase (SOD) fusion of TAT was proved to be radioprotective in our previous work. On that basis, a bifunctional recombinant protein which was the fusion of glutathione S-transferase (GST), SOD, and TAT was constructed and named GST-TAT-SOD. Herein we report the investigation of the cytotoxicity, cell-penetrating activity, and in vitro radioprotective effect of GST-TAT-SOD compared...

The radioprotective effects of dimethyl sulfoxide (DMSO) have been known for many years, and the suppression of hydroxyl (OH) radicals induced by ionizing radiation has been thought to be the main cause of this effect. However, the DMSO concentration used was very high, and might be toxic, in earlier studies. In the present study, we administered a lower, non-toxic concentration (0.5%, i.e., 64...

Radioprotective effects of ethanolic extracts Gongronema latifolium leaf against radiation induced oxidative stress in Wistar albino Rats

BACKGROUND/OBJECTIVES Exposure of the normal lung tissue around the cancerous tumor during radiotherapy causes serious side effects such as pneumonitis and pulmonary fibrosis. Radioprotectors used during cancer radiotherapy could protect the patient from side effects induced by radiation injury of the normal tissue. Delphinidin has strong antioxidant properties, and it works as the driving forc...

radiation damage is to a large extent caused by overproduction of reactive oxygen species (ros). radioprotectors are agents or substances that reduce the effects of radiation in healthy normal tissues while maintaining the sensitivity to radiation damage in tumor cells. radioprotectors are agents or substances that reduce the effects of radiation in healthy normal tissues while maintaining the ...

background: critical macromolecules of cells such as dna are in exposure to damage of free radicals that induced from the interaction of ionizing radiation with biological systems. selenium and vitamin-e are natural compounds that have been shown to be a direct free radical scavenger. the aim of this study was to investigate the radioprotective effect of selenium and vitamin-e separately and sy...

Radiation damage is to a large extent caused by overproduction of reactive oxygen species (ROS). Radioprotectors are agents or substances that reduce the effects of radiation in healthy normal tissues while maintaining the sensitivity to radiation damage in tumor cells.Radioprotectors are agents or substances that reduce the effects of radiation in healthy normal tissues while maintaining the s...