PlXDOSO: TO assess the possible role Of experimental uveitogenic antigens (S-Ag, IRPB and recoverin) in human uveitis. Methods : Patients suffering from non-infectious bilateral UVeitiS and from the Ocular type of Behcet's disease were included in this study. Patients’ lymphocytes were tested for their possible in vitro anamnestic immune ~~SpClllS~ (specific blast transformation) to S-Ag, IRBP ...

PlXDOSO: TO assess the possible role Of experimental uveitogenic antigens (S-Ag, IRPB and recoverin) in human uveitis. Methods : Patients suffering from non-infectious bilateral UVeitiS and from the Ocular type of Behcet's disease were included in this study. Patients’ lymphocytes were tested for their possible in vitro anamnestic immune ~~SpClllS~ (specific blast transformation) to S-Ag, IRBP ...

It has been shown that changes in fatty acid turnover are an early event in the response in vitro of animal lymphocytes to mitogens (Resch & Ferber, 1972). Fatty acids added to the medium in ethanol inhibit the increase in uridine and thymidine uptake in human lymphocytes, which is a normal part of the response (Meriin ef al., 1974). We have previously reported that even when bound to albumin, ...

The expression of the CD69 antigen on CD4 T lymphocytes after in vitro stimulation with purified protein derivative (2 tuberculin units) was used to evaluate the tuberculin reactivities of 52 individuals from four experimental groups: Mycobacterium bovis BCG-vaccinated healthy individuals with a negative tuberculin skin test (TST) result (group A), BCG-vaccinated healthy individuals with a posi...

PlXDOSO: TO assess the possible role Of experimental uveitogenic antigens (S-Ag, IRPB and recoverin) in human uveitis. Methods : Patients suffering from non-infectious bilateral UVeitiS and from the Ocular type of Behcet's disease were included in this study. Patients’ lymphocytes were tested for their possible in vitro anamnestic immune ~~SpClllS~ (specific blast transformation) to S-Ag, IRBP ...

An immunological glomerulonephritis was induced in dogs by the administration of rabbit anti-canine glomerular serum (1 mg/kg) and the effects on white cells in blood, thoracic duct lymph and peripheral renal lymph were observed over 14 days. The principal response was seen in the renal lymph which showed, within 1 hr of the injection of antiserum, a significant increase in its cellular content...

We tested the hypothesis that the intensity of specific antichlamydial T cell-mediated immunity in the genital tract of female guinea pigs infected intravaginally with the chlamydial agent of guinea pig inclusion conjunctivitis would determine the resistance or susceptibility to reinfection after a primary chlamydial infection. T cell-enriched lymphocytes were isolated by collagenase treatment ...

PlXDOSO: TO assess the possible role Of experimental uveitogenic antigens (S-Ag, IRPB and recoverin) in human uveitis. Methods : Patients suffering from non-infectious bilateral UVeitiS and from the Ocular type of Behcet's disease were included in this study. Patients’ lymphocytes were tested for their possible in vitro anamnestic immune ~~SpClllS~ (specific blast transformation) to S-Ag, IRBP ...

The reduced capacity of patients with multiple myeloma to respond to antigen challenge is well recognized. Response to antigen involves antigen recognition, cell proliferation, and synthesis and secretion of antibody. This study examines this sequence of events in peripheral blood lymphocytes from untreated and treated patients with myeloma, from individuals with benign monoclonal gammopathy, a...

Ultrastructural cytochemical changes occurring during the blast phase of chronic myelocytic leukemia (CML) are described. Normal developing promyelocytes contain myeloperoxidase (MPO) -positive rough endoplasmic reticulum, nuclear envelope, and Golgi apparatus. All secretory granules of normal promyelocytes are also MPO-positive. In this study we have found abnormal promyelocytes with MPO-posit...