magnetic nanoparticles are the good choice for using in mri as the contrast agent. iron oxide particles such as magnetite (fe3o4) or its oxidized form maghemite (γ-fe2o3) are the most commonly employed in biomedical applications. in this study, we synthesized and optimized the preparation of chitosan manganese-ferrite nanoparticles (cmn-fe nps) and evaluated its ability for the mice macrophage ...

Polymorphonuclear granulocytes (PMN; or neutrophils) from uninfected or human immunodeficiency virus-infected subjects were tested for their ability to inhibit growth of Candida albicans and produce interleukin-1 beta (IL-1 beta) and IL-6 in vitro. It was seen that PMN from AIDS (Centers for Disease Control stage IV) patients expressed equal if not greater anticandidal activity compared with th...

INTRODUCTION To investigate susceptibility to leprosy reactions, three polymorphisms of the natural resistance-associated macrophage protein (NRAMP1) gene were determined in 201 individuals who were attended at two reference centers in Recife, between 2007 and 2008. Of these, 100 were paucibacillary and 101 were multibacillary. METHODS The 274C/T, D543N and 1729+55del4 polymorphisms of the NR...

Human cytomegalovirus (HCMV) causes significant morbidity in the immunocompromised host. Following primary infection, the virus establishes latent infection in progenitor cells of the myeloid lineage. These cells exhibit limited viral gene transcription and no evidence of de novo virion production. It is well recognized that differentiation of latently infected myeloid progenitor cells to dendr...

it   was   recently   demonstrated   that   5-(5-nitrofuran-2-yl)-1,   3,   4-thiadiazoles   with piperazinyl-linked benzamidine substituents are effective in vitro against leishmania major. following on this evidence, we used colorimetric assay of acid phosphatase activity in the promastigotes  as  an  indicator  for  cell  viability.  also  we  studied  the  effect  of  these compounds on ind...