Diffusion-weighted imaging (DWI) is the most effective component of the modern multi-parametric magnetic resonance imaging (mpMRI) scan for prostate pathology. DWI provides the strongest prediction of cancer volume, and the apparent diffusion coefficient (ADC) correlates moderately with Gleason grade. Notwithstanding the demonstrated cancer assessment value of DWI, the standard measurement and ...

OBJECTIVES The content and distribution of lipids is an important aspect of plaque vulnerability, but lipids are present within a heterogeneous environment, impeding detection by magnetic resonance imaging. Our goal was to achieve accurate detection of mobile lipids by a single magnetic resonance imaging sequence. METHODS AND RESULTS Carotid endarectomy specimens (n=23) were imaged ex vivo at...

conclusion our preliminary results have shown that although there is some overlap between benign and malignant tumors, adding dwi, mr imaging to routine soft tissue tumor protocols may improve diagnostic accuracy. results there was only one patient with a malignant cystic tumor and was not included in the statistical analysis. the median adc values of benign and malignant tumors were 2.31 ± 1.2...

Cholesteatoma is a collection of keratinous debris and stratified squamous epithelium. It is trapped in the middle ear and can lead to bony erosion. The disease is treated surgically often followed by a second-look procedure to check for residual tissue or recurrence. Cholesteatoma has specific signal-intensity characteristics on magnetic resonance imaging with very high signal intensity on dif...

BACKGROUND AND PURPOSE Diffusion-weighted magnetic resonance imaging (DWI) can quantitatively display focal brain abnormalities within minutes after the onset of ischemia. We performed the present study to determine the effects of 1 and 2 hours of temporary ischemia on DWI. METHODS We examined DWI and T2-weighted magnetic resonance images (T2WI) during and after 1 and 2 hours of temporary mid...

Positron emission tomography with 18-fluoro-2deoxy-glucose (FDG-PET) is widely accepted as an imaging modality of choice in tumor staging. Diffusionweighted magnetic resonance imaging (DWI) has been used to detect the restricted diffusion of water molecules. The principals of DWI exploit the random motion, or so-called Brownian movement, of water molecules in biologic tissue (Le Bihan et al., 1...

basic physical principles of nuclear magnetic resonance imaging (n.m.r.i), a nonionizing medical imaging technique, are described. principles of nmri with other conventional imaging methods, ie, isotope scanning, ultrasonography and radiography have been compared. t1 and t2 and spin density (s.d.) factors and different image construction techniques based on their different combinations is discu...

The current evidence regarding the usefulness of whole-body diffusion-weighted magnetic resonance imaging (DWI) in lymphoma is reviewed. DWI is capable of combining anatomical and functional information and is becoming a valuable tool in oncology, in particular for staging purposes. DWI may prove to be a useful biomarker in clinical decision making for patients with lymphoma. Large-scaled prosp...

Magnetic resonance imaging (MRI) is a well-established imaging modality which is used in all districts of the musculoskeletal and peripheral nerve systems. More recently, initial studies have applied multiparametric MRI to evaluate quantitatively different aspects of musculoskeletal and peripheral nerve diseases, thus providing not only images but also numbers and clinical data. Besides H and P...