Human infections with Plasmodium knowlesi have been misdiagnosed by microscopy as Plasmodium malariae due to their morphological similarities. Although microscopy-identified P. malariae cases have been reported in the state of Sarawak (Malaysian Borneo) as early as 1952, recent epidemiological studies suggest the absence of indigenous P. malariae infections. The present study aimed to determine...

Haptoglobin (Hp) polymorphism and its relationship to malaria infections was examined in Solomon Islanders under 25 years of age. The slide positive rate for malaria was 48% (53/111): Plasmodium vivax (Pv) 21 cases, Plasmodium falciparum (Pf) 16 cases and the remaining 16 were a mixture of Pv/Pf/P. malariae. Of 111 subjects examined, 17% (19 subjects) were ahaptoglobinemic (HpO). No association...

A microscopy-based diagnosis is the gold standard for the detection and identification of malaria parasites in a patient's blood. However, the detection of cases involving a low number of parasites and the differentiation of species sometimes requires a skilled microscopist. Although PCR-based diagnostic methods are already known to be very powerful tools, the time required to apply such method...

We produced a hybridoma secreting an immunoglobulin G1 monoclonal antibody against the circumsporozoite protein of the human malaria parasite Plasmodium malariae (Uganda 1/CDC). The monoclonal antibody produces a circumsporozoite precipitation reaction when incubated with viable sporozoites of P. malariae and reacts at high titers with heat-fixed sporozoites in an indirect immunofluorescent ant...

Parasites are engaged in an eternal arms race with their hosts, with to man (Lalremruata et al., 2015). Surveying remote indigenous comboth sides continually reacting and adapting to try to either maintain or eliminate infection. One outcome of this coevolutionary struggle can be host species-specificity, where continued cycles of adaptation essentially isolate a parasite within a given host, p...

Citation: Muktikesh Dash. “Malaria Vaccine Development: A Step Towards Reality”. EC Microbiology 2.3 (2015): 294-295. Malaria, a protozoan parasitic disease caused by five species of Plasmodium i.e., P. vivax, P. falciparum, P. malariae, P. ovale and P. knowlesi in humans. Nearly half of the world’s population, an estimated 3.3 billion people in 97 countries and territories are at risk of malar...

Introduction: Plasmodium knowlesi (P. knowlesi), zoonotic malaria cases had been increasing in trend Terengganu, Malaysia. This study aimed to determine the associated factors of P. among registered Terengganu from 2011 September 2019 via Vekpro Online Database. Methods: A cross-sectional was conducted using extracted database and secondary weather data Malaysian Meteorological Department. tota...

In Japan, malaria has been successfully eradicated but imported malaria is still a great problem. Blood samples of malaria patients were collected from different hospitals of Japan. The samples were diagnosed by PCR based Microtiter plate-hybridization technique (MPH). The results of MPH were compared with microscopic diagnosis done at the laboratories of different hospitals. Among the total 23...

We report an unusual case of transfusion-transmitted malaria which remained undiagnosed for several months in an Italian woman splenectomised and polytransfused for thalassaemia major. The infecting species was Plasmodium malariae, and the patient developed acute renal failure, severe thrombocytopenia, and hepatic failure. Treatment with chlorochine was followed by a slow, but complete recovery...

background: malaria is the most important transfusion-transmitted infection (tti) in worldwide after viral hepatitis and human immunodeficiency virus (hiv) infection. the main objective of the present study was to review and evaluate the transmission of malaria via blood transfusion in iran. methods : a literature search was done without time limitation in the electronic databases as follows: p...