A bioassay for possible carcinogenicity of technical-grade hexachloroethane was conducted using Osborne-Mendel rats and B6C3F1 mice. Hexachloroethane in corn oil was administered by gavage, at either of two dosages, to groups of 50 male and 50 female animals of each species. The chemical was administered 5 days a week, cyclically for 44 of 78 weeks in rats and continuously for 78 weeks in mice,...

This study aims to investigate the effect of xylopia aethiopica on the sexual behavior of adult male rats. Fort eight adult male wistar rats were used for the study. They were randomly divided into four groups of 6 animals each: group 1 was control, while groups 2, 3 and 4 were test groups treated daily with 0.5, 2 and 10 mg/kg body weight respectively of hydro-methanolic fruit extract...

Activation of poly(ADP-ribose) polymerase (PARP) is an important factor in the pathogenesis of various cardiovascular and inflammatory diseases. Here, we report that the gender-specific inflammatory response is preferentially down-regulated by PARP in male animals. Female mice produce less tumor necrosis factor-alpha and macrophage inflammatory protein-1alpha in response to systemic inflammatio...

Glycyrrhiza glabra extract is gaining increasing acceptance as a folk remedy for treatment of wound. We studied the effect of its extract on wound tensile strength in albino rats. 20 male albino rats had a linear 3 cm incision made over skin of back. The animals were randomly divided into two experimental groups, as control and treatment. Animals of control group received topical cold cream onc...

background: matricaria chamomilla (chamomile) is a herb used to treat various human illnesses. the present study was conducted to investigate the effects of chamomile extract on spermatozoon quality, serum levels of estradiol and testosterone, and sperm tail length in male adult rat .   methods: male sprague-dawley rats received extract of chamomile (400 mg/kg once daily, orally) during an 8-we...

BACKGROUND Cisplatin (CP) as a potential drug for solid tumors produces nephrotoxicity and disturbs endothelial function. CP induced nephrotoxicity may be gender related. Nitric oxide plays a pivotal role in endothelial function and L-arginine as endogenous NO donor promotes endothelial function. The role of L-arginine in CP induced nephrotoxicity model and its gender related was investigated i...

Glycyrrhiza glabra extract is gaining increasing acceptance as a folk remedy for treatment of wound. We studied the effect of its extract on wound tensile strength in albino rats. 20 male albino rats had a linear 3 cm incision made over skin of back. The animals were randomly divided into two experimental groups, as control and treatment. Animals of control group received topical cold cream onc...

Ticks are ectoparasites (Hematophagous) of wild and domestic animals. These hazardous especially livestock industry all around the world, most ticks species have been caused huge economic losses to animals as well industry. The current study was conducted check prevalence taxonomic identification tick in Tehsil Sinjawi. In 2020 2021 such Rhipicephalus Hyalomma belonging two genera were collecte...

The gene virilizer (vir) is needed for dosage compensation and sex determination in females and for an unknown vital function in both sexes. In genetic mosaics, XX somatic cells mutant for vir differentiate male structures. One allele, vir2f, is lethal for XX, but not for XY animals. This female-specific lethality can be rescued by constitutive expression of Sxl or by mutations in msl (male-spe...