Fibrous histiocytomas represent 1% of all orbital masses and may be classified into benign, locally aggressive and malignant - these representing nearly 11% of the total. In this study, the authors describe an unusual case of malignant fibrous histiocytoma of the eyelid, discussing clinical and histological features of this neoplasm.

Fibrous dysplasia is a condition leading to abnormal differentiation of osteoblasts which leads to replacement of normal bone with fibrous stroma [1-3]. It may involve single bone (monostotic) or multiple bones (polyostotic). It may affect any bone however; skull and ribs are the commonest [2,4-6]. It is usually asymptomatic and is an incidental finding. It may become symptomatic when complicat...

Malignant fibrous histiocytoma (MFH) is one of the most common adult soft tissue sarcomas. MFH is very aggressive and is most often found in the extremities and the retroperitoneum, but it can manifest at other sites. Though the lungs are the most common sites of metastasis, they rarely present there as a primary tumor. Our report describes a rare case of a primary MFH tumor in the lung. Carefu...

Malignant fibrous histiocytoma is a rare neoplasm composed of fibroblasts and histiocytes. It assumes several histologic forms, which account for its various names and the difficulty in its diagnosis and classification. A case thought to be the sixth malignant fibrous histiocytoma involving the larynx is presented. The treatment of choice is wide excision with close follow-up examination.

2006;130;581-583 Chest Massimiliano Paci and Alberto Cavazza Giulio Rossi, Laura Schirosi, Filippo Giovanardi, Giuliana Sartori, ß Mutation PDGFR With Sarcomatous Overgrowth Showing Pleural Malignant Solitary Fibrous Tumor http://chestjournal.org/cgi/content/abstract/130/2/581 and services can be found online on the World Wide Web at: The online version of this article, along with updated infor...

A 60-year-old man, with a history of hypercholesterolemia and left leg deep vein thrombosis, was admitted to hospital following two weeks of headaches and expressive aphasia. Neurological examination confirmed expressive aphasia in the absence of motor, sensory or cranial nerve deficit. A total body computer tomography (CT) imaging showed a single intraparenchymal lesion with a central necrotic...

We read with great interest a recently published article by Lecoutere et al [1] entitled “multifocal cytokeratin expression in pleural and abdominal malignant solitary fibrous tumor: an unusual diagnostic pitfall”. Authors showed three histologically and immunohistochemically welldocumented cases of pleural and abdominal malignant solitary fibrous tumor (SFT) with unexpected multifocal expressi...

Introduction  Benign fibrous histiocytomas are common lesions of the skin that rarely affect the tongue. Such cases are available in the literature exclusively as case reports. Similarly, malignant fibrous histiocytoma, now classified as undifferentiated pleomorphic sarcoma, is exceedingly rare in the tongue and not fully understood. Objectives  This study systematically reviews the available l...

Malignant fibrous histiocytoma (MFH) cases are classified within the group of nonclassified sarcomas. The etiopathogenesis is unclear; however, MFH commonly develops in scar tissue and in areas exposed to radiation. MFH is the most common soft tissue sarcoma in adults and may be borne in the lungs, chest wall, mediastinum, or other tissues. Primary MFH of the lung constitutes less than 0.2% of ...

Primary intraabdominal malignant mesenchymal tumors are very rare. There are just few cases of intraabdominal visceral malignant fibrous histiocytoma in the literature. We report a case of primary malignant fibrous histiocytoma of the spleen in a 57-year-old man, with a recurrence eight years after the splenectomy. After the initial surgery the patient was without complaints, and refused to rec...