1. The formation of thromboxane B, and malondialdehyde was studied in human plateletrich plasma, in gel-filtered platelets and in bovine platelet microsomes. 2. Exogenous sodium arachidonate was converted into thromboxane B, and malondialdehyde in a concentr ation-dependent manner. Pre-incubation of platelets with aspirin inhibited the production of both thromboxane B, and malondialdehyde, alth...

BACKGROUND Emerging science has shown the effect of oxidation products and inflammation on atherogenesis and carcinogenesis. Cooking hamburger meat can promote the formation of malondialdehyde that can be absorbed after ingestion. OBJECTIVE We studied the effect of an antioxidant spice mixture on malondialdehyde formation while cooking hamburger meat and its effects on plasma and urinary malo...