Background and objectives: Hemorrhoids is the most painful rectal disease. Straining and pregnancy seem playing chief roles in the development of hemorrhoids. Symptoms of hemorrhoids may include bleeding, inflammation and pain. Despite current medical efforts, many discomforts of hemorrhoids have not been handled. The aim of the present study was to formulate and evaluate I...

Flexible manufacturing systems (FMS) require efficient scheduling strategies to achieve their principal advantage of being able to combine high flexibility with high productivity. This paper presents a novel constraint programming (CP) formulation addressing the FMS scheduling problem for systems that work under the operational policy of part movement. The formulation addresses some critical fe...

A common approach to increase reliability and efficiency of manufacturing systems is optimal scheduling. In this paper, we consider scheduling problems for a specific type of systems where batch processes are running in parallel. The goal is to schedule the interaction between the parallel processes, in the form of energy flows, to minimize a desired objective. We make use of a max-plus approac...

Consider the optimal control of a manufacturing system consisting of stages in which a single consumable good is produced in a random jump environment. At each stage of the manufacturing process there are workstations that can fail and be repaired. The workstations are assumed to have different operating parameters for a given stage. The mean time to failure for a given workstation, on a given ...

Consider a manufacturing system in which a single consumable good is fabricated in a process that consists of stages in an uncertain environment. On each stage, there are a number of workstations that are assumed to have different operating parameters that are subject to failure, repair, and preventive maintenance which generate discrete jumps in the value of the state. A Just-In-Time manufactu...

3.1 Description and composition ....................................................................................... 4 3.2 Formulation development and characterization ........................................................... 4 3.2.1 Pharmaceutical development ............................................................................... 4 3.2.2 Characterization of drug products ............

Vibrations with unknown and/or time-varying frequencies significantly affect the achievable performance of control systems, particularly in precision engineering and manufacturing applications. This paper provides an overview of disturbance-observer based adaptive vibration rejection schemes; studies several new results in algorithm design; and discusses new applications in semiconductor manufa...

We introduce a methodology for automated production planning of semiconductor manufacturing based on iterative linear programming (LP) optimization and discrete-event simulation calculations. The LP formulation incorporates epochdependent parameters for flow times from lot release up to each operation on each manufacturing route. LP-derived release schedules are used as input to the simulation ...

There has recently been an increased emphasis on reducing energy consumption in manufacturing, driven by the fluctuations in energy costs and the growing importance given to environmental impact of manufactured goods. Lots of attention has been given to the reduction of machine tools energy consumption, as they require large amounts of energy to perform manufacturing tasks. One area that has re...

We are witnessing the emergence of a new paradigm in the modeling of material structures. It stems from the digitization of manufacturing and is fueled by advances in additive manufacturing and material science. This paper strives to provide a critical examination of this new paradigm in a historical and tech­ nological context and to show that it requires non-trivial extensions and generalizat...