background: pancytopenia is a manifestation of a wide range of disorders. the main prognostic factor for predicting outcome and response to treatment is based on the underlying cause. to detect the root cause of this problem, depending on other accompanied signs or symptoms, the need for bone marrow examination and other advanced work ups is different at least at the practical level. this study...

background: bone marrow transplant (bmt) recipients are prone to bacterial, viral and fungal infections. bacterial infec­tion is considered as one of the common and serious complications in bone marrow transplant recipients. the aim of this study was to determine the rate of bacterial infections in bone marrow transplant recipients. methods: fifty-two blood and 25 catheter samples were obtained...

background: radiation therapy is an effective method used for treatment of many types of cancers. however, this method can cause unwanted side effects such as bone marrow suppression. in this study, the effect of oral administration of biogenic selenium nanoparticles (senps) on total and differentiated white cells profile of balb/c mice exposed to x-ray radiation was investigated and compared w...

background differences in causes, severities, areas of stenosis, and the association with swallowing and phonation of larynx and trachea can result into laryngotracheal stenosis (lts).this study evaluated the healing effect of bone marrow stem cells (bmscs) in experimentally induced lts dog model. methods seven dogs were enrolled. bmscs were isolated from proximal humerus and shoulder of a dog ...

background: bone marrow stromal cells (bmsc) have been successfully employed for movement deficit recovery in spinal cord injury (sci) rat models. one of the unsettled problems in cell transplantation is the relative high proportion of cell death, specifically after neural differentiation. according to our previous studies, p75 receptor, known as the death receptor, is only expressed in bmsc in...

background: bone marrow stromal stem cells (bmsc) are appropriate source of multipotent stem cells that are ideally suited for use in various cell-based therapies. it can be differentiated into neuronal-like cells under appropriate conditions. this study examined the effectiveness of co-stimulation of creatine and retinoic acid in increasing the differentiation of bmsc into gabaergic neuron-lik...

background: adipose-derived stem cells (adsc) could be an appealing alternative to bone marrow stem cells (bmsc) for engineering cell-based osteoinductive grafts. meanwhile, prior studies have demonstrated that melatonin can stimulate osteogenic differentiation. therefore, we assayed and compared the melatonin effect on osteogenic differentiation of bmsc with that of adsc. methods: mesenchymal ...

generation neural stem cells from neurosphere–derived bone marrow stem cells using bioactive substance atc. bone marrow cells (bmscs) were isolated from rat. bmscs cultured by dmem/f12 medium supplemented with 10% fetal bovine serum. these cells evaluated by specific markers of bmscs such as bioactive substance atc, b27. then bmscs differentionated in to neurosphere and divided in two groups wh...

conclusions due to the high risk of non-:union: and mal-:union: in humerus shaft fracture, and because applying this simple and inexpensive technique significantly decreased these complications, injecting autologous bone marrow grafts is recommended for accelerating :union: in cases of humerus fracture. results the mean time of :union: was 8.54 ± 3.41 weeks for the individuals followed in the s...