OBJECTIVE To assess the family history of diabetes in type 2 black South African diabetics with emphasis on the parental phenotype. DESIGN Prospective case-control study in which family histories were obtained from patients. SETTING Diabetic clinic of a provincial teaching hospital in the Transkei region of South Africa. SUBJECTS A total of 1111 type 2 diabetics attending the diabetic cli...

Background: Gestational diabetes is one of the most common complications of pregnancy that has several effects on mother and baby. Objectives: The aim of this study was to examine the prevalence as well as maternal and neonatal outcomes in women with gestational diabetes. Methods: This descriptive comparative study was carried out on all pregnant women who underwent 75 g glucose test and refe...

BACKGROUND The UK Biobank study provides a unique opportunity to study the causes and consequences of disease. We aimed to use the UK Biobank data to study the well-established, but poorly understood, association between low birthweight and type 2 diabetes. METHODS We used logistic regression to calculate the odds ratio for participants' risk of type 2 diabetes given a one standard deviation ...

BACKGROUND Little is known about early life determinants of non-alcoholic fatty liver disease (NAFLD). We examined associations of maternal pregnancy diabetes/glycosuria and pre-pregnancy body mass index (BMI) with offspring markers of NAFLD and liver pathology and examined mediation by birthweight and concurrent offspring adiposity. METHODS We used data from a UK prospective pregnancy cohort...

objective: to compare maternal complications and labor outcome in obese and non-obese women. materials and methods: it is a retrospective comparative study conducted at the department of obstetrics and gynecology, unit 1, civil hospital, karachi from december 2008 to december 2009. a sample size of 220 gravid women is selected by non probability convenience sampling technique. in these 110 obes...

OBJECTIVE To investigate the impact of selected maternal chronic medical conditions, race, and age on preterm birth (PTB), low birth weight (LBW), and infant mortality among Mississippi mothers from 1999 to 2003. DESIGN A retrospective cohort analysis of linked birth and death certificates. SAMPLE The 1999-2003 Mississippi birth cohort comprising 202,931 singleton infants born to African Am...

BACKGROUND The purposes of this study were to explore whether the maternal-fetal outcomes differed among various types of hyperglycemia during pregnancy and whether the values of glycemic screening in the middle phase of pregnancy could predict maternal-fetal outcomes. METHODS A retrospective study was conducted to study the incidence of maternal-fetal outcomes in 383 singleton pregnant women...