Neonatal Graves' disease presenting as conjugated hyperbilirubinemia is a diagnostic challenge because the differential includes a gamut of liver and systemic diseases. We present a unique case of neonatal Graves' disease in a premature infant with conjugated hyperbilirubinemia born to a mother with hypothyroidism during pregnancy and remote history of Graves' disease. Infant was treated with a...

Endocrine disorders are common in patients with Prader-Willi syndrome (PWS). Whether hypothyroidism is present PWS, and especially infants young children, remains unclear. The aims of this study were to evaluate thyroid function assess the prevalence dysfunction, effect growth hormone on function. Subjects 23 PWS ages 3 months years who followed for up one year. Four lost follow-up after first ...

Background Subclinical hypothyroidism is a common endocrine disorder during pregnancy, associated with adverse maternal and fetal outcomes. This study aimed to evaluate the frequency of subclinical among pregnant women who presented our hospital between 2020 2022. Methods A retrospective chart review was conducted on 589 using convenience sampling. Only underwent thyroid function testing had no...

Adequate maternal iodine consumption during pregnancy and lactation guarantees normal thyroid hormones (TH) production, which is crucial to the development of the fetus. Indeed, iodine deficiency is clearly related to maternal hypothyroidism and deleterious effects in the fetal development. Conversely, the effects of iodine excess (IE) consumption on maternal thyroid function are still controve...

Objectives: Thyroid problems are one of the endocrine conditions that affect pregnant women most frequently. It is now widely acknowledged both overt and subclinical thyroid can have a negative impact on obstetrical neonatal outcomes. Surprisingly, there aren't many statistics from India regarding prevalence disease during pregnancy. The purpose this study to ascertain frequency dysfunction in ...

Introduction: Congenital hypothyroidism is a preventable cause of intellectual disability in childhood. It one the commonest endocrine conditions encountered neonatal period. Maternal Thyroid Status has long been recognized as having an impact on developing fetus, and more recently family history thyroid dysfunction implicated risk factor congenital (CH). Therefore, this study focused screening...

We recently reported that TRH-deficient mice showed characteristic tertiary hypothyroidism. In the present study, we investigated how this tertiary hypothyroidism occurred particularly in pre- and postnatal stages. Immunohistochemical analysis revealed a number of TSH-immunopositive cells in the TRH-/- pituitary on embryonic day 17.5 and at birth. The mutant pituitary at birth in pups born from...

Several recent publications have drawn attention to the role of the thyroid hormone status of the mother on the future neuropsychological development of the child. The screening of pregnant women for clinical or subclinical hypothyroidism based on second trimester elevated maternal TSH values has been proposed. Here, we have summarized present epidemiological and experimental evidence strongly ...