Thymus-derived lymphocyte precursors (pre-T cells) 1 are found in adult mammalian bone marrow. The precursor nature of the cells can be demonstrated by their ability to reconstitute the thymus of irradiated recipients (1). This procedure is tedious, not easily quantitated, and only rarely applicable to humans. Fortunately, another assay for pre-T cells has recently been described: in the presen...

The aim of this work was to determine in Capsicum chinense the 1) concentration heavy metals (Al, As, Cd, Pb), majority (Ca, K, Mg, Na) and essential (Cu, Fe, Mn, Se, Zn) mineral elements, 2) effects ripening stage, harvest number type soil on content 3) authenticity markers. Peppers grown black red soils Mayan region, were harvested two stages (ripe peppers [orange green peppers, respectivily]...

Epidermal stem cells control the homeostasis and regeneration of skin hair through their ability to self-renew for extended periods time differentiation into multiple lineages. KROX20, a zinc finger-containing transcription factor, mediates signaling pathways modulate cell activation quiescence in various tissues. In recent study, we identified population epithelial-derived Krox20-expressing up...

B-cell maturation antigen is expressed on plasma cells. In this study, we have identified serum B-cell maturation antigen as a novel biomarker that can monitor and predict outcomes for multiple myeloma patients. Compared to healthy donors, patients with multiple myeloma showed elevated serum B-cell maturation antigen levels (P<0.0001). Serum B-cell maturation antigen levels correlated with the ...

background: fat-rich diet may alter oocyte development and maturation and embryonic development by inducing oxidative stress (os) in follicular environment. objective: to investigate the relationship between fat intake and oxidative stress with oocyte competence and embryo quality. materials and methods: in observational study follicular fluid was collected from 236 women undergoing assisted re...

Tumors produce a number of immunosuppressive factors that block the maturation of CD34+ stem cells into dendritic cells (DC). We hypothesized that tumors might also interfere with the maturation and/or function of human monocyte-derived DC. In contrast to stem cells, we found that CD14+ cells responded to tumor culture supernatant (TSN) by increasing expression of APC surface markers, up-regula...

Recent studies suggest that multivesicular bodies are an intermediate stage in the formation of alpha-granules. In contrast, the kinetics and mode of appearance of dense granules during megakaryocytic maturation has remained poorly understood. Immunoelectron microscopy was used to monitor the appearance of dense granular markers (granulophysin and serotonin) on cryosections of human megakaryocy...

Under endoplasmic reticulum (ER)-stress conditions, the unfolded protein response (UPR) generates a defense mechanism in mammalian cells. The regulation of UPR signaling is important in oocyte maturation, embryo development, and female reproduction of pigs. Recent studies have shown that melatonin plays an important role as an antioxidant to improve pig oocyte maturation. However, there is no r...

................................................................................................................................ 1 1 Literature Review ............................................................................................................... 2 1.1 Kainate Receptors ........................................................................................................ 2 1.1...

background: the effect of temperature and humidity on the maturation of toxocara cati eggs in an in vitro system was investigated. methods: suspensions of toxocara cati eggs, with 5% formalin/saline or 2.5% formalin/ringer were prepared and maintained at 37 °c under 40% humidity or at 25 °c under 98% humidity for 3 weeks for egg development. results: the suspension sample mixed by 2.5% formalin...