A chitinase was purified from Vitis vinifera Manzoni Bianco grape juice and characterized. On the basis of proteomic analysis of tryptic peptides, a significant match identified the enzyme as a type IV grape chitinase previously found in juices of other V. vinifera varieties. The optimal pH and temperature for activity toward colloidal chitin were found to be 6 and 30 °C, respectively. The enzy...

Genetic mapping studies have suggested that diploid cotton (Gossypium) might be an ancient polyploid. However, further evidence is lacking due to the complexity of the genome and the lack of sequence resources. Here, we used the grape (Vitis vinifera) genome as an out-group in two different approaches to further explore evidence regarding ancient genome duplication (WGD) event(s) in the diploid...

The effects of induced mutation produced by five different doses of gamma irradiation (20, 25, 30, 40, and 45 Gy) were determined using molecular approaches in Vitis vinifera cultivars, namely Thompson Seedless (Sultani Çekirdeksiz) (progenitor of seedless vinifera variety) and Kalecik Karasi (one of the best quality wine grape variety of Turkey). Mutant candidates were selected through morphol...

Koshu is a grape cultivar native to Japan and is one of the country's most important cultivars for wine making. Koshu and other oriental grape cultivars are widely believed to belong to the European domesticated grape species Vitis vinifera. To verify the domesticated origin of Koshu and four other cultivars widely grown in China and Japan, we genotyped 48 ancestry informative single nucleotide...

Background: Peptic ulcer disease is a most common disease, whose incidence is increasing presently on account of demanding stressful life. Objectives: To evaluate and compare the antiulcer activity of the extracts of seed and skin of Vitis Vinifera (Grape) using two different doses (100 & 200 mg/kg). Methods: The extracts of seed and skin of Vitis Vinifera were investigated for their anti-ulcer...

The skin constitutes the first barrier between our organism and the environment. The epidermis consists mainly by keratinocytes that play an essential role in epidermal renewal and skin's defence, actively participating in the cutaneous immune responses through the expression of a variety of cytokines/chemokines. Despite their protective role, keratinocytes are also relevant to the pathogenesis...

Biological Functions of Some Key Bioactive Compounds Grapes (Vitis vinifera L.) in the Prevention Breast Cancer: A Narrative Review

T he wine grape, Vitis vinifera, is a member of the Vitaceae, a family of vigorous, climbing, woody plants that live in the Northern Hemisphere. The plants are illadapted to tropical climates, and thus never crossed the equator (except those transported by humans, which are cultivated in Argentina, Chile, Australia, South Africa, and other regions in the Southern Hemisphere). The genus Vitis co...

objective: grape virus diseases are a serious problem in iran. leaves and fruits of grape have been used for different purposes like cooking in iran. the present investigation was carried out to study on the cytotoxic-activities of extracts of fruits and leaves of vitis vinifera from both virus-free and virus-infected grape cultivars against breast cancer cell line (mda-mb-231) and human embryo...