A case report of a multidrug-resistant (MDR) infection with a strain of Klebsiella pneumoniae carrying a novel metallo-b-lactamase (MBL), the New Delhi MBL (NDM-1), appears in this issue of Clinical Infectious Diseases [1]. Sidjabat and colleagues detail the presentation and susceptibility profile and give us a brief molecular characterization of an isolate of K. pneumoniae carrying blaNDM-1 th...

Background: Acinetobacter baumannii, is an opportunistic pathogen and is responsible for numerous nosocomial infections. In recent years, this microorganism has been resistant to a wide range of antibiotics. One of the most important mechanisms of resistance in this microorganism is production of metallo-beta-lactamases (MBLs). Objectives: The aim of this study was to detect VIM- and IMP-type ...

In todays technologically-driven educational landscape, mobile learning systems (MBL) have progressively risen to become critical tools for effective education delivery in many rural schools. Like most developing countries, the sector Zimbabwe plays a role facilitating human capital development and economic growth development. However, country’s secondary schools are still lagging behind urban ...

Metallo-β-lactamases (MBLs) in Enterobacteriaceae are an increasing problem worldwide. This report describes the isolation of Citrobacter freundii carrying IMP-8 MBL from three patients during the period from March 2012 until March 2013 in Germany. The bla IMP-8 enzyme is predominantly found in Asia, where IMP-8 has spread to various enterobacterial species causing serious infections. To our be...

background: acinetobacter baumannii, is an opportunistic pathogen and is responsible for numerous nosocomial infections. in recent years, this microorganism has been resistant to a wide range of antibiotics. one of the most important mechanisms of resistance in this microorganism is production of metallo-beta-lactamases (mbls). objectives: the aim of this study was to detect vim- and imp-type m...

Aim: In this study, we evaluated the presence of antibiotic resistance genes among P. aeruginosa strains. Methodology: From January to September 2012, 100 isolates of P. aeruginosa were collected from burn patients. Antimicrobial susceptibility testing was performed by disk diffusion method. Screening for Metallo-β-lactamases (MBLs) productions were performed by Combination Disk Diffusion Test ...

The recognition of pathogens is mediated by a set of pattern recognition molecules that recognize conserved pathogen-associated molecular patterns shared by broad classes of microorganisms. Mannose-binding lectin (MBL) is one of the pattern recognition molecules and activates complement in association with MBL-associated serine protease (MASP) via the lectin pathway. Recently, an MBL-like lecti...

BACKGROUND Metallo-beta-lactamase (MBL) producing Pseudomonas aeruginosa has emerged as a threat to hospital infection control, due to its multi-drug resistance, especially in intensive care units (ICUs). AIMS This study was carried out to detect MBL producing P. aeruginosa isolates from medical and surgical ICUs, to compare and evaluate different phenotypic methods currently in use and to de...

BACKGROUND The aim of this study was to investigate the molecular epidemiological characteristics of metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa clinical isolates in Korea. MATERIALS AND METHODS Three hundred and twenty nine P. aeruginosa clinical isolates were collected from 23 general hospitals in Korea from March to June 2014. Species were identified by matrix-assited laser ...