Burst fractures are common fractures resulting from impact loading and can have severe consequences such as neurological deficits [1]. The biomechanical process which leads to burst fracture is still debated. Finite element models (FEM) could further our knowledge on burst fracture mechanism. A precise evaluation of the mechanical properties of bone tissues is a critical issue when creating the...

Additively manufactured (AM) micro-architected biodegradable metals offer a unique combination of properties that are ideal for bone regeneration including biocompatibility, fully interconnected porous structure, and the possibility to regenerate bony defects with native tissue upon biodegradation. Currently, mechanical AM can only match values human trabecular bone, hindering their application...

statement of problem: impacts and accidents are considered as the main fac- tors in losing the teeth, so the analysis and design of the implants that they can be more resistant against impacts is very important. one of the important nu- merical methods having widespread application in various fields of engineering sciences is the finite element method. among its wide applications, the study of ...

The purpose of this study was to determine the influence of alpha-ketoglutarate (AKG) daily administration via the digestive tract on cortical bone loss. Due to structural and physiological properties, the study was executed on humerus model in turkey. The neurectomy of the radial and mediano-ulnar nerves was applied to induce osteopenic effect in the right humerus. The experiment was conducted...

Whereas there is clear evidence for a strong influence of bone quantity (i.e., bone mass or bone mineral density) on vertebral mechanical behavior, there are fewer data addressing the relative influence of cortical and trabecular bone microarchitecture. The aim of this study was to determine the relative contributions of bone mass, trabecular microarchitecture, and cortical thickness and curvat...

Introduction: Human cortical bone has been demonstrated as an anisotropic material. It has been shown that nanoindentation can be used to quantitatively reveal the anisotropy of cortical bone with the fact that different indentation modulus could be obtained at different indentation directions [1]. However, since nanoindentation analysis is developed based on isotropic material properties, test...

Effects of long-term tennis loading on volumetric bone mineral density (vBMD) and geometric properties of playing-arm radius were examined. Paired forearms of 16 tennis players (10 women) and 12 healthy controls (7 women), aged 18-24 yr, were scanned at mid and distal site by using peripheral quantitative computerized tomography. Tomographic data at midradius showed that tennis playing led to a...

Biglycan (bgn) is a small leucine-rich proteoglycan (SLRP) enriched in the extracellular matrix of skeletal tissues. While bgn is known to be involved in the growth and differentiation of osteoblast precursor cells and regulation of collagen fibril formation, it is unclear how these functions impact bone's geometric and mechanical properties, properties which are integral to the structural func...

Recent advancements in magnetic resonance imaging (MRI) have enabled clinical imaging of human cortical bone, providing a potentially powerful new means for assessing bone health with molecular-scale sensitivities unavailable to conventional X-ray-based diagnostics. To this end, (1)H nuclear magnetic resonance (NMR) and high-resolution X-ray signals from human cortical bone samples were correla...