Transcription of C-reactive protein (CRP) in Hep 3B cells is induced by IL-6, acting through C/EBP isoforms and STAT3. IL-1beta, which alone has no effect, greatly enhances IL-6-induced transcription by unknown mechanisms. Because IL-1beta activates the NF-kappaB system, we explored the effects of overexpressed Rel family members on CRP expression. Unexpectedly, transactivation assays in transi...

The paper introduces a family of three-DOFs translationalrotational Parallel-Kinematics Mechanisms (PKMs) as well as the mobility analysis of such family using Lie-group theory. Each member of this family has two-rotational onetranslational DOFs. A novel mechanism is presented and analyzed as a representative of that family. The use and the practical value of that modular mechanism are emphasized.

Objective(s): Ten-eleven translocation (TET) family members have been shown to be involved in the development of many tumors. However, the biological role of the TET family and its mechanism of action in colorectal carcinogenesis and progression remain poorly understood. Materials and Methods:We measured the expression levels of TET family members in colorectal cancer (CRC) specimens, in the c...

Glycocyamine kinase (GK), a member of the phosphagen kinase family, catalyzes the Mg(2+)-dependent reversible phosphoryl group transfer of the N-phosphoryl group of phosphoglycocyamine to ADP to yield glycocyamine and ATP. This reaction helps to maintain the energy homeostasis of the cell in some multicelullar organisms that encounter high and variable energy turnover. GK from the marine worm N...

introduction: health care professionals especially clinicians, undergo lots of job stress (js). emotional intelligence (ei) is among the variables that appear to be associated with stress. it is also included among the ways adopted by the individuals in order to resist js in the workplace. thus, this study aims to investigate the relationship between ei and js in the faculty members of esfahan ...

this study has been conducted with the aim of surveying the barriers and challenges of research in universities from the perspective of faculty members (islamic azad and payam-e nour, razi, medical sciences) in kermanshah done. questionnaire being used in this research is barriers and challenges from the perspective of research at universities retrieved from master thesis, it was based on liker...

This study examined the influence of various conflict management mechanisms embedded into computer-supported collaborative concept mapping systems on the behaviour and learning of elementary students. Four conflict management mechanisms were compared: an assign design, in which the mapping control was designated to a particular group member; a rotate design, in which the mapping control was rot...

in this paper, dynamical behavior of the delay mechanism of a special projectile controller is studied, using 3d finite element simulation. the controller considered here is among of high-acceleration mechanical controllers. due to high linear and angular accelerations of the projectile and also explosion risk, experimental investigation is very limited and almost impossible. so, numerical simu...