نتایج جستجو برای: mepyramine

تعداد نتایج: 164  

Journal: :Brain research. Molecular brain research 1996
L Puebla E Rodríguez-Martín E Arilla

In the present study, the effects of an intracerebroventricular (i.c.v.) dose of histamine (0.1, 1.0 or 10.0 micrograms) on the hippocampal somatostatin (SS) receptor/effector system in Wistar rats were investigated. In view of the rapid onset of histamine action, the effects of histamine on the somatostatinergic system were studied 2 h after its administration. Hippocampal SS-like immunoreacti...

Journal: :The Journal of pharmacology and experimental therapeutics 2002
Raymond G Booth Nader H Moniri Remko A Bakker Neepa Y Choksi William B Nix Henk Timmerman Rob Leurs

Previously, (-)-trans-1-phenyl-3-N,N-dimethylamino-1,2,3,4-tetrahydronaphthalene ([-]-trans-H(2)-PAT) was shown to activate stereospecifically histamine H(1) receptors coupled to modulation of tyrosine hydroxylase activity in guinea pig and rat forebrain in vitro and in vivo. Furthermore, the novel radioligand [(3)H](-)-trans-H(2)-PAT was shown to label selectively H(1) receptors in guinea pig ...

Abolghasem Jouyban, Ali Khodadadi, Ian L. Naylor, Mohammad H. Pipelzadeh,

The absence of a universally accepted mathematical model for assessment of the effectiveness of drugs in the process of wound healing is one of the problems the health professionals have been faced. In this study, an “empirical” mathematical model is presented to evaluate its reliability from an experimental viewpoint and from a comparative aspect with previous models used to study wound healin...

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