Background: Skin flap grafting is a popular approach for reconstruction of critical skin and underlying soft tissue injuries. In a previous study, we demonstrated the beneficial effects of two 5α-reductase inhibitors, azelaic acid and finasteride, on tissue survival in a rat model of skin flap grafting. In the current study, we investigated the involvement of nitric oxide and inducible nitric o...

INTRODUCTION In vascular surgery the crossover iliofemoral bypass grafting is a well-known surgical technique. In general surgery the repair of an abdominal defect using a Polypropylene mesh is also a standard procedure. A particular technique is defined by the performance of these 2 separate procedures inside a single operation in which the crossover arterial graft is directed from the retrope...

background: skin flap grafting is a popular approach for reconstruction of critical skin and underlying soft tissue injuries. in a previous study, we demonstrated the beneficial effects of two 5α-reductase inhibitors, azelaic acid and finasteride, on tissue survival in a rat model of skin flap grafting. in the current study, we investigated the involvement of nitric oxide and inducible nitric o...

o. There are two different cryopreservation protocols used in skin preservation: slow freezing and quick freezing/snap frozen. Slow freezing can be achieved using a controlled-rate cooling apparatus (Blondet et al., 1982). There is an optimum cooling rate for any cell type that produces maximum cell survival. On either side of this optimum, the survival rate falls. In the presence of CPA, a coo...

When a graft is placed on a recipient bed, the process of accepting the graft begins. For some hours, the graft is bathed and nourished by plasmatic circulation or serum imbibition. Si‐ multaneously, fortuitous and accidental apposition of the vessels in the bed and those in the graft allows blood to be sucked into the graft. Soon afterwards, active penetration of the graft by blood vessels fro...

Adaptive Cartesian mesh methods have demonstrated unique abilities for automated mesh generation and dynamic mesh adaptation to flow solution and moving boundaries. However Navier-Stokes (NS) solvers with Cartesian mesh often produce large fluctuations of surface quantities (pressure, skin friction, and heat flux) at solid boundaries. We show that the Immersed Boundary Method (IBM) with adaptiv...

Although skin grafting originated 2500 to 3000 years ago, it was until the 19 th century that this technique was again introduced as a reconstructive option. While 19th century surgeons used grafts to repair their most difficult cases, skin grafting has since evolved into a modality that is routinely and sometimes preferentially used for the surgical repair of skin defects [1]. In this chapter ...

Background. Hyperbaric oxygen (HBO) therapy, which is used for many conditions, may also have immunosuppressive effects and could be used for prevention or treatment of graft-versus-host disease (GvHD). If HBO is immunosuppressant, then we hypothesize that HBO therapy will delay the T-cell mediated skin graft rejection. Methods. C57/BL6 black-coated (H2B) mice received skin graft from CBA (H2D)...

BACKGROUND Split- thickness skin graft is one of the most common operations in plastic surgery. It is always painful and patient discomfort from donor site often is more significant than recipient site. There is not still a standard method for treatment of the donor site. The purpose of this study was to determine the best method of dressing the donor site among three different methods with res...

BACKGROUND The treatment of chronic lesions in hidradenitis suppurativa (HS) remains a challenge for dermatologists. In most cases, wide surgical excision of the affected skin reduces the recurrence rate to a minimum. Split-thickness skin grafts have usually been applied to resurface large postoperative defects. OBJECTIVE. : The aim of this study is to introduce an alternative method of skin gr...