نتایج جستجو برای: metabolic stress
تعداد نتایج: 638913 فیلتر نتایج به سال:
Cells that grow together respond heterogeneously to stress even when they are genetically similar. Metabolism, a key determinant of cellular stress tolerance, may be one source of this phenotypic heterogeneity, however, this relationship is largely unclear. We used self-establishing metabolically cooperating (SeMeCo) yeast communities, in which metabolic cooperation can be followed on the basis...
OBJECTIVE To examine the relationships among negative attributions of friend reactions (NAFRs) within a social context, anticipated adherence difficulties, diabetes stress, and metabolic control. RESEARCH DESIGN AND METHODS A sample of 104 adolescents with type 1 diabetes completed instruments measuring demographics, attribution of friend reactions, anticipated adherence, and diabetes stress....
The unfolded protein response (UPR) is linked to metabolic dysfunction, yet it is not known how endoplasmic reticulum (ER) disruption might influence metabolic pathways. Using a multilayered genetic approach, we find that mice with genetic ablations of either ER stress-sensing pathways (ATF6alpha, eIF2alpha, IRE1alpha) or of ER quality control (p58(IPK)) share a common dysregulated response to ...
in india, a survey indicates the prevalence of 30 times increase in hypertension among urban dwellers, compared with 10 times in rural inhabitants. 1 urbanization together with a change in life style, diet, and job stress, has been attributed in causing hypertension.stress can cause hypertension by elevating the blood pressure (bp) and by stimulating the nervous system leading to the production...
BACKGROUND Previous research has shown that metabolic syndrome as well as early life stress can account for immunoactivation (e.g. in the form of altered fibrinogen levels) in patients with major depression. This study aims at assessing the relationship between components of metabolic syndrome, early life stress and fibrinogen levels, taking the severity of depression into consideration. SUBJ...
Background and Objectives: Metabolic syndrome (MetS) is one of the most common diseases and a public health problem in most populations and predisposes to many metabolic disorders such as type 2 diabetes. Inflammatory processes and oxidative stress are the important factors in pathogenesis of MetS. Also, the effect of sex, race, age, nutrition and life style is very important in incidence of th...
Background: High oxidative stress in pregnant women leads to pathogenesis or progression of disease in newborns. The aim of this study was to investigate the Effect of Endurance Training in Maternal Metabolic Syndrome with Metformin on Oxidant and antioxidant Capacity in their Neonates. Methods: To implementation of this experimental research, 16 female Wistar rats weighing 100 ± 20 gr randoml...
Metabolomics analysis of wild type Arabidopsis thaliana plants, under control and drought stress conditions revealed several metabolic pathways that are induced under water deficit. The metabolic response to drought stress is also associated with ABA dependent and independent pathways, allowing a better understanding of the molecular mechanisms in this model plant. Through combining an in silic...
Background and Objective: It seems that war veterans are at increased risk of cardiovascular diseases due to their existing disabilities and special mental and psychological conditions. This study was performed to evaluate the risk of cardiovascular disease and the prevalence of metabolic syndrome among Iran-Iraq war veterans living in Zanjan in 2011. Materials and Methods: 360 men including 12...
OBJECTIVE Fibroblast growth factor 21 (FGF21) was recently discovered as stress-induced myokine during mitochondrial disease and proposed as key metabolic mediator of the integrated stress response (ISR) presumably causing systemic metabolic improvements. Curiously, the precise cell-non-autonomous and cell-autonomous relevance of endogenous FGF21 action remained poorly understood. METHODS We ...
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