A series of metalloporphyrin dimers were modularly prepared and shown to catalyze the methanolysis of a phosphate triester, yielding rates that are large compared to the rate of the uncatalyzed reaction. Up to 1300-fold rate acceleration can be achieved via a combination of cavity-localized Lewis-acid activation and methoxide-induced methanolysis.

A general method for synthesizing a novel class of metalloporphyrin dimers containing unbridged metal-metal bonds is presented. By choosing the appropriate metal, the bond order in these dimers can be varied systematically. The synthesis and characterization of osmium(II) and molybdenum(II) porphyrin dimers containing the respective metal-metal double and quadruple bonds are described. A simple...

Metalloporphyrins (MP) and metallophtalocyanines (MPc) are innovative materials with catalytic properties that have attracted attention for their application diverse electrochemical purposes. The presence of metallic centers in structure offers a redox-active behavior is being applied the design solid electrodes quantification biomolecules, water contaminants, pharmaceuticals, among others. Her...

Metalloporphyrins are exceedingly useful building blocks for the design and synthesis of molecularly based solids. The use of hydrogen bonding or metal ion coordination provides a wide range of framework solids. Using various polyfunctionalized porphyrins, we have created porous solids that are thermally robust and that retain their internal porosity upon loss of solvates. Their pore dimensions...

Major advances have been made towards efficient catalytically active model systems for cytochrome P-450 during these last ten years. Some recent developments of this field are described. This include (i) examples of application of these biomimetic systems to compounds of biological interest, (ii) the use of Mn-porphyrins to catalyze the transfer of a nitrogen atom into organic substrates, and (...

Synthetic metalloporphyrins, in the presence of monooxygen donors, are known to mimetize various reactions of cytochrome P450 enzymes systems in the oxidation of drugs and natural products. The oxidation of piperine and piplartine by iodosylbenzene using iron(III) and manganese(III) porphyrins yielded mono- and dihydroxylated products, respectively. Piplartine showed to be a more reactive subst...