Background and Objective: Breast cancer is the second leading cause of cancer-related death in women. Better individualized treatment needs novel prognostic predictors. X-ray repair cross complementing XRCC5 and XRCC6 are coding genes of the Ku protein complex (key components of the non-homologous end-joining [NHEJ] pathway), which could serve as prognostic factors in breast cancer. Hence, in t...

Apalutamide is a non-steroidal selective androgen receptor inhibitor approved for the treatment of high-risk non-metastatic castration-resistant prostate cancer and metastatic hormone-sensitive cancer. The paper describes case patient diagnosed with long-term course disease. was stage 18 years after primary treatment. Systemic apalutamide recommended. Initially, carried out as part extended acc...

colorectal cancer remains one of the major cancer- related deaths despite progress in the treatment during past decades. detection of disease at earlier stages reduces its mortality. the aim of current study was to investigate expression of cytokeratin 19 (ck19), cytokeratin 20 (ck20) and guanylyl cyclase c (gcc) mrna in peripheral blood of non- metastatic colorectal cancer patients which may r...

background: contralateral axillary metastasis (cam) is a rare entity in patients with breast cancer which can occur during the primary breast cancer or its follow-up. different treatment modalities include surgery, radiotherapy, and chemotherapy, but there is no agreement on them. in our review, we found 12 series with available data, 82 patients with synchronous or metachronous contralateral a...

Abstract Abdominal wall metastases are rarely seen in primary colorectal cancer; the majority of cases attributed to seeding from previous procedures. We report a case percutaneous cryoablation metastatic cancer abdominal with no evidence recurrence 1 year later.

introduction: thermal ablation by microwave (mwa) has proven efficacy in treatment of primary and metastatic cancers. soft tissue tumors could be ablated completely using mwa. however, bony tissue metastasis particularly spinal vertebral metastasis ablation has not reported yet. case presentation: a 50 year old male patient with primary diagnosed colon cancer undergone surgical resection of tum...

Craniofacial skeletal metastasis is a rare presentation of advanced prostate cancer. This is a report of a 69-year-old man who presented with numbness of the right lower lip and recently ill-fitting lower denture. Based on the medical history of benign prostate hyperplasia (BPH) and suspicion of a metastatic tumor, prostate core needle biopsy was performed. Histology of the prostate biopsy con...

Objective(s): The growing trend of research demonstrates that dynamic expression of two metastasis repressor classes (metastasis suppressor genes and anti-metastatic miRNA) has a close relationship with tumor invasion and metastasis. Using different strategies, it was revealed that cellular levels of miR-31 and Breast cancer Metastasis Suppressor1 (BRMS1) protein, whic...

Parenchyma–preserving hepatic resection in treatment of metastatic colorectal cancer: analysis the literature data and own experience accumulated