A simple, rapid, and sensitive high-performance liquid chromatographic method was developed and validated for determination of tadalafil, a selective and reversible phosphodiesterase inhibitor, in human serum. Methylparaben was used as the internal standard. Optimum conditions for tadalafil assay were investigated. The analyte and internal standard were extracted by a single-step liquid–liquid ...

An HPLC method with amperometric detection was developed for analysis of two local anesthetics (lidocaine and benzocaine) in products for delaying ejaculation illegally marketed in Polish sex shops. Chromatographic elution on an RP column C18 with mobile phase composed of acetate buffer with acetonitrile, provides an optimal separation not only of active substances but also electroactive preser...

In this study, a PoL/RGO material was successfully synthesized and employed to modify the working electrode for determining MPB in medication products through voltammetric techniques. The structure of nanocomposite characterized by UV–vis FT-IR spectrum its application electrochemical detection tested CV DPV result, modified PoL-RGO/GCE exhibited superior response toward applying method, compar...

The impacts of chlorination on methylparaben (MP) removal, as well bromide and ammonia the MP elimination kinetics, were studied. Bromide react with chlorine are promptly transformed into bromine chloramines, respectively. Rate constants chlorine, bromine, monochloramine determined under different pH conditions. At 8.5, apparent second-order rate reactions found to be 3.37(±0.50) × 101 2.37 (±0...

Previous studies have shown that the exfoliation of graphitic carbon nitride (g-C3N4) is essential to obtain materials with good photocatalytic properties. However, in most works influence exfoliation...

A chemical study on the n-BuOH-soluble fraction of the 95% EtOH extract of red yeast rice fermented with the fungus Monascus pilosus BCRC 38093 (Eurotiaceae) has resulted in the isolation of one new natural pyrrole derivative, designated as monascuspyrrole (1) together with nine known compounds, 3β-hydroxystigmast-5-en-7-one (2), β-sitostenone (3), monascin (4), ankaflavin (5), N-trans-feruloyl...