The plasma levels of soluble antiapoptotic Fas (sFas) and proapoptotic Fas-ligand (sFasl) proteins were studied in heart transplant recipients at one-month follow-up. The patients were treated with Neoral (n=18) or Tacrolimus (n=12) and concomitant immunosuppressive drugs. The sFas and sFasl levels were detected by ElISA. The values were related to treatment with Neoral or Tacrolimus in stable ...

Background: The use of high-dose steroid therapy peri portoenterostomy may have a positive impact on the frequency of cholangitis and survival rate. Methods: A prospective study was conducted on two groups of patients (less than three months of age) suffering from biliary atresia from 1999 to 2005. The patients in group I (G I) were managed peri-operatively by high-dose methylprednisolone while...

Purpose: Through observing the effect of high-dose methylprednisolone treatment on active AS with acute anterior uveitis (AAU) to evaluate the influence of methylprednisolone on the serological cytokines IL-23 and IL-17 in AS patients with AAU. We try to explore the clinical effect and possible mechanism of high-dose methylprednisolone treatment on AS with AAU. Methods: The present study includ...

It has been shown that a prolonged low-dose corticosteroid treatment attenuates the severity of inflammation and the intensity and duration of organ system failure. In the present study, we determined whether low-dose methylprednisolone (a synthetic glucocorticoid) can protect male Wistar rats against cardiac pumping defects caused by lipopolysaccharide-induced chronic inflammation. For the ind...

134 patients with Age-related Macular Degeneration (AMD) (aging 47-75 years) were treated in therapy procedure with parabulbar injections of Methylprednisolone Acetate and Prednisolone Acetate. In the first group of patients with AMD (n = 71 patients) were treated with Methylprednisolone acetate, and second group (n = 63 patients) with Prednisolone acetate. Each patient was given doses of 60 mg...

OBJECTIVE To investigate the effect of injecting the methylprednisolone in the ear for the sudden deafness and the improvement of speech discrimination test. METHODS 50 inpatients with a sudden hearing loss were recruited. Inject the methylprednisolone in the subperiosteal of the ear which is 0.5 cm distance to the ear ditch every three days. Methylprednisolone was placed for fifteen days. Si...