BACKGROUND Pomaglumetad methionil (LY2140023 monohydrate) is a potent and highly selective agonist for the metabotropic glutamate mGluR2 and mGluR3 receptors. We present results of a pivotal clinical study H8Y-MC-HBBM assessing the efficacy of LY2140023 in improving symptoms as a monotherapy in patients with an acute exacerbation of schizophrenia. METHODS Enrolled adult patients (ages 18-65) ...

PURPOSE To determine whether a combination of L-methylfolate, methylcobalamin, and pyridoxal-5'-phosphate (LMF-MC-PLP [Metanx; Pamlab LLC, Covington, La]) improves sensory neuropathy. RESEARCH DESIGN AND METHODS This multicenter, randomized, double-blind, placebo-controlled trial involved 214 patients with type 2 diabetes and neuropathy (baseline vibration perception threshold [VPT]: 25-45 vo...

INTRODUCTION The study analyzes the effect of an advanced access program on quality of diabetes care. METHODS We conducted this study in a medical group of 240,000 members served by 17 primary care clinics. Seven thousand adult patients older than 18 years of age with diabetes were identified from administrative databases. Two aspects of advanced access - wait time for appointments and contin...

A total of 1,023 environmental surfaces were sampled from 45 rooms with patients infected or colonized with methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-resistant enterococci (VRE) before terminal room cleaning. Colonized patients had higher median total target colony-forming units (CFU) of MRSA or VRE than did infected patients (median, 25 CFU [interquartile range, 0-106 CF...

Chimeric antigen receptor T-cell therapy (CAR T) is a novel intervention for relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) and other hematologic malignancies. However, it associated with prolonged toxicity (PHT) that unpredictable can significantly impair patients' quality of life. Reported here single-center experience PHT in adult patients R/R DLBCL who received commercial CAR...

H. Newsom, D. Panda, M. S. Sisodia and A. Dube, Indian Institute of Geomagnetism, Navi Mumbai410 218, India ([email protected]); Institute of Meteoritics and Department of Earth and Planetary Sciences, University of New Mexico, Albuquerque, NM 87131, USA ([email protected]); Physical Research Laboratory, Ahmedabad380 009, India; Dept. of Geology, J. N. Vyas University, Jodhpur342 033, India ...

Matthew Choptuik, Luis Lehner, Ignacio ~Iñaki! Olabarrieta, Roman Petryk, Frans Pretorius, and Hugo Villegas CIAR Cosmology and Gravity Program, Canada Department of Physics and Astronomy, University of British Columbia, Vancouver, Canada V6T 1Z1 Department of Physics and Astronomy, Louisiana State University, Baton Rouge, Louisiana 70810, USA Theoretical Astrophysics 130-033, California Instit...

Qiang Zhang, 2 Xiang-Bin Wang, Yu-Ao Chen, Tao Yang, and Jian-Wei Pan 2 Hefei National Laboratory for Physical Sciences at Microscale & Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026, P.R. China Physikalisches Institut, Universität Heidelberg, Philosophenweg 12, 69120 Heidelberg, Germany 3 Imai Quantum Computation and Information Project, ERATO,...