Microarrays produces enormous amounts of information requiring a series repeated analyses to condense data. To analyze this data several computational software is used. Objective: compare the analysis R and Mathematica package for differential gene expression using microarray dataset. Methods: Microarray Data were collected from an online database GEO (gene omnibus). was used comparative analys...

Although HPV infection is clearly implicated in the pathogenesis of undifferentiated PeIN and PeSCC, role MGLSc differentiated remains unclear. Whilst prevalence most studies reported as ≥20%, this number largely reflects latency not transcriptional activity. Formalin-fixed, paraffin-embedded blocks penile tissue from 94 patients with MGLSc, (MGLSc-related) (HPV-related) PeIN, well disease-adja...

A series of exciting reports over the past two years has established the usefulness of protein chips and made important advances in preparing protein arrays. However, several technical challenges must still be addressed to make these tools available to the wider community of researchers. Here, we discusses these challenges and survey recent opportunities for creating quantitative assays, prepar...