Naphthalene (NA) is metabolized to highly reactive intermediates that are primarily detoxified by conjugation to glutathione (GSH). Intraperitoneal administration of naphthalene causes substantial loss of both hepatic and respiratory GSH, yet only respiratory tissues are injured in mice. The liver supplies GSH to other organs via the circulation, making it unclear whether respiratory GSH losses...

Naphthalene AA-Final, a naphthalene preparation, is a new tool in the management of psoriasis. Brown naphthalene has been used for 15 years in the treatment of psoriasis at Special Hospital for Medical Rehabilitation in Ivanic Grad, Croatia. Naphthalene is obtained from naphtha, a complex mixture of various compounds, mostly hydrocarbons. Naphthalene AA-Final is a new naphthalene preparation en...

Previous studies have shown variability in naphthalene cytotoxicity, expression of CYP2F2 gene and protein, and naphthalene metabolism in random cycling female mice (NIH:Swiss). CYP2F2 metabolizes naphthalene to cytotoxic metabolites in lungs of mice. This study was designed to address the question: do hormonal changes associated with the estrous cycle alter metabolism of naphthalene in the lun...

Previous studies have shown variability in naphthalene cytotoxicity, expression of CYP2F2 gene and protein, and naphthalene metabolism in random cycling female mice (NIH:Swiss). CYP2F2 metabolizes naphthalene to cytotoxic metabolites in lungs of mice. This study was designed to address the question: do hormonal changes associated with the estrous cycle alter metabolism of naphthalene in the lun...

Previous studies have shown variability in naphthalene cytotoxicity, expression of CYP2F2 gene and protein, and naphthalene metabolism in random cycling female mice (NIH:Swiss). CYP2F2 metabolizes naphthalene to cytotoxic metabolites in lungs of mice. This study was designed to address the question: do hormonal changes associated with the estrous cycle alter metabolism of naphthalene in the lun...

Naphthalene, a constituent of coal tar, is a contaminant frequently found at former manufactured gas plants (MGP). Development at these sites has resulted in residential and commercial areas with potential exposures from vapor intrusion adversely affecting indoor air of residences and buildings. Naphthalene is routinely analyzed in soil vapor intrusion assessments for properties overlying and s...

Naphthalene (CAS Registry Number: 91-20-3) is a natural constituent of coal tar, comprising approximately 11% of that material by weight (HSDB, 2003). It is present in gasoline and diesel fuels. All pesticide registrations of naphthalene, including use as a moth repellent, were cancelled in California in 1991 due to data gap inadequacies. However, naphthalene is included on a list of "inert" or...

The research was focused on the slurry-phase biodegradation of naphthalene in soil. Among ex situ techniques, the slurry phase offers the advantage of increased availability of contaminants to bacteria. From naphthalene contaminated soil, a Pseudomonas putida M8 strain capable to degrade naphthalene was selected. Experiments were performed in a stirred and oxygenated reactor. In this study, the...

Cold and dense samples of naphthalene (C(10)H(8)) are produced using buffer gas cooling in combination with rapid, high flow molecule injection. The observed naphthalene density is n approximately 10(11) cm(-3) over a volume of a few cm(3) at a temperature of 6 K. We observe naphthalene-naphthalene collisions through two-body loss of naphthalene with a loss cross section of sigma(N-N) = 1.4 x 1...

Naphthalene, the most common polycyclic aromatic hydrocarbon, causes airway epithelium injury in mice. Repeated exposure of mice to naphthalene induces airway epithelia that are resistant to further injury. Previous studies revealed that alterations in bioactivation enzymes and increased levels of gamma-glutamylcysteine synthase in the bronchioles protect tolerant mice from naphthalene and its ...