نتایج جستجو برای: microfluidic biochips
تعداد نتایج: 18179 فیلتر نتایج به سال:
Microfluidics-based biochips are soon expected to revolutionize biosensing, clinical diagnostics and drug discovery. Robust off-line and on-line test techniques are required to ensure system dependability as these biochips are deployed for safety-critical applications. Due to the underlying mixed-technology and mixed-energy domains, biochips exhibit unique failure mechanisms and defects. We fir...
BACKGROUND Multiple locus sequence typing (MLST) has become a central genotyping strategy for analysis of bacterial populations. The scheme involves de novo sequencing of 6-8 housekeeping loci to assign unique sequence types. In this work we adapted MLST to a rapid microfluidics platform in order to enhance speed and reduce laboratory labor time. METHODOLOGY/PRINCIPAL FINDINGS Using two integ...
With the advancement of digital microfluidics technology, applications such as on-chip DNA analysis, point of care diagnosis and automated drug discovery are common nowadays. The use of Digital Microfluidics Biochips (DMFBs) in disease assessment and recognition of target molecules had become popular during the past few years. The reliability of these DMFBs is crucial when they are used in vari...
The limited availability of primary human ?-cells/islets and their quality (due to donor diversity) restrict the development in vitro models for diabetes research. Human induced pluripotent stem cells (hiPSCs) may be a promising cell-source studies, anti-diabetic drug screening personalized therapies. However, achieving levels maturity/functionality that are comparable vivo situation islets reb...
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